Analysis of the functions of microRNAs in host immune responses to infection with Leishmania major
| Project/Area Number |
22590382
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SHIMODA Koji 慶應義塾大学, 医学部, 准教授 (00129470)
KIMURA Tokuhiro 慶應義塾大学, 医学部, 助教 (40445200)
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| Research Collaborator |
FUKAO Taro Max-Planck-Institute of Immunobiology, Freiburg, GERMANY, 主任研究員 (20401127)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | microRNA / Leishmania major / 感染症 / 遺伝子欠損マウス / 免疫学 / 国際情報交換 / ドイツ |
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| Research Abstract |
To clarify a role of microRNA in host immune system, gene-targeted microRNA-deficient mice (BALB/c background; miR-/-) were immunologically analyzed after infection with Leishmania major (L.major). Whereas BALB/WT mice developed progressive non-healing le
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Report
(4 results)
Research Products
(8 results)
