| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
Catecholamine, including norepinephrine (NE), has been known as precipitating factor in bacterial infection. The aim of this study was to clarify the pathogenic activation mechanism of pathogenic bacteria that cause the catecholamine, to help infectious diseases treatment.
In this study, we analyzed using Vibrio parahaemolyticushave been studying the applicant is consistently. V.parahaemolyticusinfection can be thought of as an exemplary model of intestinal bacterial infections in general. We searched for the presence of receptors for NE on the surface in V.parahaemolyticus. And we analyzedof the regulatory mechanism and expression pathogenic gene by the NE furtherin V.parahaemolyticus. .
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