Study on consumers/patients' preference to breast cancer care

• Project/Area Number: 22590451
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical sociology
• Research Institution: University of Tsukuba
• Principal Investigator: KONDO Masahide 筑波大学, 医学医療系, 准教授 (70334068)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 医療経済学 / 乳癌 / 健常者 / 患者 / 選好 / 需要 / 効用値 / 経済評価 / クオリティ・オブ・ライフ / 社会医学 / 医療・福祉 / 癌 / 乳癌医療

Research Abstract

This study aimed to estimate health related quality of life for health states of postoperative primary breast cancer patients using time trade-off technique. 275 females were selected from the panel members of a web survey company. They were asked to respond to time trade-off questions after receiving an explanation for 8 postoperative health states by combining the type of primary breast surgery, the type of axillary lymph node treatment and adjuvant endocrine therapy. 8 utility weights ranging from 0.444 to 0.627 were obtained. These results will increase the validity of future economic evaluations of breast cancer care in Japan.

Research Products

• [Journal Article] Economic evaluation of the 70-gene prognosis-signature (MammaPrint(R)) in hormone receptor-positive, lymph node-negative, human epidermal growth factor receptor type 2-negative early stage breast cancer in Japan (2012)
  • Author(s): Kondo M、Hoshi SL、Ishiguro H、To i M
  • Journal Title: Breast Cancer Research and Treatment Volume: 133巻 Issue: 2 Pages: 759-758
  • DOI: 10.1007/s10549-012-1979-7
  • Peer Reviewed
• [Journal Article] Economic evaluation of the 21-gene signature (Oncotype DX(R)) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TR03) (2011)
  • Author(s): Kondo M、Hoshi SL、Yamanaka T、Ishiguro H、Toi M
  • Journal Title: Breast Cancer Research and Treatment Volume: 127巻 Issue: 3 Pages: 739-749
  • DOI: 10.1007/s10549-010-1243-y
  • Peer Reviewed
• [Journal Article] Economic evaluation of the 21-gene signature (Oncotype DX(R)) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TRO3) (2010)
  • Author(s): Kondo M, Hoshi SL, Yamanaka T, Ishiguro H, Toi M
  • Journal Title: Breast Cancer Research and Treatment Volume: 130巻
  • Peer Reviewed
• [Presentation] 原発性乳癌患者術後のQuality of Life:時間得失法による効用値の推定 (2012)
  • Author(s): 近藤正英
  • Organizer: 第71回日本公衆衛生学会総会
  • Place of Presentation: サンルート国際ホテル山口、山口市
  • Year and Date: 2012-10-25
• [Presentation] 原発性乳癌患者のQuality of Life：時間得失法による効用値の推定 (2012)
  • Author(s): 近藤正英
  • Organizer: 第７１回日本公衆衛生学会総会
  • Place of Presentation: 山口
• [Presentation] Development of a prediction model for treatment response to neoadjuvant chemotherapy in patients with primary breast cancer using a decision-tree algorithm (2012)
  • Author(s): Naito Y, Bando H, Iwata H, Kuroi K, Masuda N, Ohno S, Sato N, Kondo M, Sasano H, Inaraoto T, Tomita M
  • Organizer: Society of Surgical Oncology 65th Annual Cancer Symposium
  • Place of Presentation: 米国、フロリダ州、オーランド
• [Presentation] Utility of a prediction model for axillary lymph node metastasis in patients with primary breast cancer using a decision-tree algorithm (2012)
  • Author(s): Takada M, Sugimoto M, Naito Y, Moon H, Han W, Noh D, Kondo M, Kuroi K, Sasano H, Inamoto T, Tomita M, Toi M
  • Organizer: Society of Surgical Oncology 65th Annual Cancer Symposium
  • Place of Presentation: Orlando world center Mariott (USA)
• [Presentation] Development of a clinical prediction model for axillarylymph node metastasis in primary breast cancer patients-a validation study and a literature review (2011)
  • Author(s): Takada M, Sugimoto M, Naito Y, Moon HG, Han W, Noh DY, Kondo M, Kuroi K, Sasano H, Inamoto T, Tomita M, Toi M
  • Organizer: Global Breast Cancer Conference 2011
  • Place of Presentation: 大韓民国、ソウル
• [Presentation] 高リスク乳癌患者に対する予防的G-CSF併用第3世代化学療法レジメンの医療経済学的評価に関する研究 (2010)
  • Author(s): 中村清吾, 手良向聡, 柳原一広, 戸井雅和
  • Organizer: 日本乳癌学会
  • Place of Presentation: ロイトン札幌(北海道)
  • Year and Date: 2010-06-25
• [Book] 乳癌レビュー2012 (2012)
  • Author(s): 戸井雅和,他
  • Publisher: メディカルレビュー社
• [Book] 乳癌レビュー2012 (2012)
  • Author(s): 戸井雅和
  • Total Pages: 295
  • Publisher: メディカルレビュー社