Establishment of an objective method for the effect of dietary supplements applying neurological and cardiological tests

Research Project

Project/Area Number	22590546
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Hygiene
Research Institution	Akita University
Principal Investigator	IWATA Toyoto 秋田大学, 大学院・医学系研究科, 助教 (00321894)
Co-Investigator(Kenkyū-buntansha)	MURATA Katsuyuki 秋田大学, 大学院・医学系研究科, 教授 (80157776)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords	健康食品 / 長鎖不飽和脂肪酸 / ドコサヘキサエン酸 / アラキドン酸 / 手のふるえ / 心拍変動 / QT時間 / DHA / RR間隔 / QTc / 心臓自律神経 / 神経運動機能 / 食品衛生 / 神経生理機能 / 不飽和脂肪酸 / ベンチマークドース
Research Abstract	Dietary supplements, suppliers claim their beneficent effect to certain physiological functions, should be examined beforehand for their safety and effects. We tried to work out an example of such functional test applying objective and valid methods that have been used for neurological evaluations especially in environmental sciences. Aimed supplement was docosahexaenoic acid (DHA), a kind of essential fatty acids we usually take from fish. A remarkable result was that, among persons taking DHA, there was tendency of decrease in tremor intensity as the serum arachidonic acid concentration increased.