Analysis of the skin cancer induced by ultraviolet
Project/Area Number |
22590558
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Hygiene
|
Research Institution | Chubu University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
KATO Masashi 名古屋大学, 医学部, 教授 (10281073)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 皮膚ガン / 紫外線 / 悪性黒色腫 / 皮膚がん / 皮膚癌 |
Research Abstract |
We analyzed the down-regulation gene with tumor progression in melanoma. UV radiation down-regulates expression of the gene in murine benign tumor. Down-regulation of the gene was observed with tumor progression in human melanoma. Expression of the gene in melanoma decreased cell growth and invasive ability. These results suggested that the gene may prevent progression of melanoma.
|
Report
(4 results)
Research Products
(6 results)