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Basic epidemiological research for the purpose of nutrition therapy guidelines creation of amyotrophic lateral sclerosis

Research Project

Project/Area Number 22590595
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionAichi Prefectural University

Principal Investigator

OKAMOTO KAZUSHI  愛知県立大学, 看護学部, 教授 (60148319)

Co-Investigator(Kenkyū-buntansha) EGAMI Isuzu  名古屋文理大学, 健康科学部, 教授 (00367848)
FUJIWARA Nakako  愛知県立大学, 看護学部, 教授 (30178032)
KIHIRA Tameko  関西医療大学, 保健医療学部, 教授 (30225015)
ISHII Eiko  椙山女学園大学, 看護学部, 教授 (50367695)
Project Period (FY) 2010-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords筋萎縮性側索硬化症 / 栄養調査 / 症例対照研究 / 神経難病 / 栄養療法 / 疫学研究 / 栄養摂取 / 栄養指針 / IT機器
Research Abstract

In both the nutritional survey for ALS patients and case-control study to clarify nutritional factors associated with an increased risk of ALS, ALS patients had a higher intake of carbohydrate, and a lower intake of total energy, and fat and protein than controls. Proportion of subjects with less frequent intake (less than once a week) of protein-rich foods such as beans, dairy products, egg, and antioxidants-rich foods such as green-yellow vegetables and fruits were higher in deterioration in clinical status than in no deterioration in clinical status. Taking these findings into account, we created nutrition therapy guidelines of amyotrophic lateral sclerosis as follows; 1) Increase of intake of total food, 2) Decrease in carbohydrate intake and increase in fat and protein intake, 3) Increase in antioxidants-rich foods such as green-yellow vegetables and fruits.

Report

(6 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Products Report
  • Research Products

    (14 results)

All 2014 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (10 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Journal Article] Basic epidemiological research for the purpose of nutrition therapy guidelines creation of amyotrophic lateral sclerosis2014

    • Author(s)
      Kazushi Okamoto
    • Journal Title

      International Innovation

      Volume: 153 Pages: 17-19

    • Related Report
      Products Report
  • [Journal Article] 映画鑑賞会の交流会を通して人口呼吸器装着しているALS患者の市民への啓発事業報告2012

    • Author(s)
      石井英子、岡本和士、藤原奈佳子
    • Journal Title

      医学と生物学

      Volume: 156 Pages: 151-157

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] スレート型PCを用いた高齢者のための簡易栄養管理システムの使用2012

    • Author(s)
      川島基子、吉野孝、江上いすず、岡本和士、藤原奈佳子、石川豊美、紀平為子、入江真行
    • Journal Title

      電子情報通信学会技術研究報告福祉工学研究会

      Volume: 111 Pages: 75-85

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 在宅療養におけるALS患者の嚥下状況とALS機能評価スケールとの関連2013

    • Author(s)
      石井英子、藤原奈佳子、岡本和士
    • Organizer
      第23回日本疫学会
    • Place of Presentation
      大阪大学コンベンションセンター(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Predictors of increase in severity among Japanese amyotrophic lateral sclerosis patients by discriminant analysis2012

    • Author(s)
      Kazushi Okamoto
    • Organizer
      23thALS/MND International Symposium
    • Place of Presentation
      Chicago
    • Related Report
      2013 Final Research Report
  • [Presentation] ALS 機能評価スケールと骨量計を用いた在宅療養ALS患者評価2012

    • Author(s)
      石井英子、藤原奈佳子、岡本和士
    • Organizer
      第71回日本公衆衛生学会
    • Place of Presentation
      山口市民会館(山口県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 料理の新規登録を考慮した高齢者のための簡易栄養管理システムの開発2012

    • Author(s)
      川島基子、吉野 孝、江上いすず、岡本和士、藤原奈佳子、石川豊美、紀平為子
    • Organizer
      第32回医療情報学連合大会
    • Place of Presentation
      朱鷺メッセ新潟コンベンションセンター(新潟県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Was Dried Fish A Trigger Of High-incidence Of Amyotrophic Lateral Sclerosis in Kii Peninsula, Japan?2012

    • Author(s)
      Okamoto K. Kihira T, Kokubo Y. Kuzuhara S
    • Organizer
      23th International Symposium on ALS/ MND
    • Place of Presentation
      Sheraton Chicago(USA(Chicago))
    • Related Report
      2012 Annual Research Report
  • [Presentation] Gender differences in the relationship between lifestyle factors and risk of amyotrophic lateral sclerosis2011

    • Author(s)
      Kazushi Okamoto
    • Organizer
      22thALS/MND International Symposium
    • Place of Presentation
      Sydney
    • Related Report
      2013 Final Research Report
  • [Presentation] 筋萎縮性側索硬化症(ALS)患者の食事状況とBMIとの関連2011

    • Author(s)
      江上いすず
    • Organizer
      日本栄養改善学会
    • Place of Presentation
      広島
    • Related Report
      2013 Final Research Report
  • [Presentation] 筋萎縮性側索硬化症発症関連要因に関する症例対照研究2011

    • Author(s)
      岡本和士
    • Organizer
      第52回日本神経学会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Final Research Report
  • [Presentation] 筋萎縮性側索硬化症(ALS)患者の食事状況とBMIとの関連2011

    • Author(s)
      江上いすず、石井英子、田中結花子、藤原奈佳子、岡本和士
    • Organizer
      日本栄養改善学会
    • Place of Presentation
      広島国際会議場
    • Related Report
      2011 Annual Research Report
  • [Presentation] 在宅療養ALS患者のためのiPadを用いた簡易栄養管理システムの開発2011

    • Author(s)
      川島基子、吉野孝、江上いすず、岡本和士、藤原奈佳子、石川豊美、紀平為子、入江真行
    • Organizer
      第31回医療情報学連合大会
    • Place of Presentation
      鹿児島市市民文化ホール
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] 元気やる気本気パン2012

    • Inventor(s)
      岡本和士
    • Industrial Property Rights Holder
      岡本和士
    • Acquisition Date
      2012-02-17
    • Related Report
      2013 Final Research Report
    • Overseas

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Published: 2010-08-23   Modified: 2019-07-29  

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