Multicenter cohort study for usefulness of speckle tracking echocardiography to predict cardiac resynchronization therapy

• Project/Area Number: 22590768
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Circulatory organs internal medicine
• Research Institution: University of Tsukuba
• Principal Investigator: SEO Yoshihiro 筑波大学, 医学医療系, 准教授 (40375499)
• Co-Investigator(Kenkyū-buntansha): ISHIZU Tomoko 筑波大学, 医学医療系, 講師 (10507859) ; AONUMA Kazutaka 筑波大学, 医学医療系, 教授 (10375488)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 臨床心血管病態学 / 心臓再同期療法 / 心臓超音波法 / 心不全 / 心エコー図法

Research Abstract

This multicenter prospective cohort study was performed to identify the usefulness of speckle tracking echocardiography that has been developed as a novel echocardiographic method in assessing responses to cardiac resynchronization therapy (CRT). Among total 187 subjects who were enrolled in this study, 99 subjects were identified as a CRT responder. This study revealed that a circumferential strain parameter by speckle tracking echocardiography was the best predictor for CRT responders. Finally, this study is the first study that contributed to identify the important role of echocardiography to predict CRT responders.

Research Products

• [Presentation] Speckle Tracking imaging for the Assessment of cardiac Resynchronization Therapy (START) study (2012)
  • Author(s): Yoshihiro Seo
  • Organizer: American Heart Association Scientific Sessions2012
  • Place of Presentation: Los Angels Convention Center, LA(USA)
  • Year and Date: 2012-11-05
• [Presentation] Speckle Tracking imaging for the Assessment of cardiac Resynchronization Therapy (START) study (Late Breaking Clinical Trials) (2012)
  • Author(s): Yoshihiro Seo
  • Organizer: 日本循環器学会等名
  • Place of Presentation: 福岡国際会議場、福岡
  • Year and Date: 2012-03-16
• [Presentation] Speckle tracking imaging for the assessment of cardiac resynchronization therapy (2012)
  • Author(s): 瀬尾由広
  • Organizer: 第76回日本循環器学会学術集会
  • Place of Presentation: 福岡国際会議場
  • Year and Date: 2012-03-16
• [Presentation] CRTを導入する心エコー指標 (2010)
  • Author(s): 瀬尾由広
  • Organizer: 日本超音波医学会講習会
  • Place of Presentation: 広島
  • Year and Date: 2010-06-27
• [Presentation] Newly depeloped 2-dimensional and 3-dimensional speckle tracking technique to quantify regional myocardial function. (2010)
  • Author(s): 瀬尾由広
  • Organizer: American Society of Echocardiography 21st Annual Scientific Sessions
  • Place of Presentation: San Diego, USA
  • Year and Date: 2010-06-14
• [Presentation] 心不全とCRT (2010)
  • Author(s): 瀬尾由広
  • Organizer: 日本不整脈学会CRT/ICDセミナー
  • Place of Presentation: 名古屋
  • Year and Date: 2010-06-10
• [Presentation] Dyssynchronyと再同期療法をめぐる新たな展開国内多施設研究の現状 (2010)
  • Author(s): 瀬尾由広
  • Organizer: 第21回日本心エコー図学会学術集会
  • Place of Presentation: 札幌
  • Year and Date: 2010-05-14
• [Remarks]
  • URL: http://tsukubadaigaku.com/tsukuba/kakennhi/seika