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Early detection of coronary artery disease using magnetocardiography

Research Project

Project/Area Number 22590769
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Circulatory organs internal medicine
Research InstitutionUniversity of Tsukuba

Principal Investigator

WATANABE Shigeyuki  筑波大学, 医学医療系, 教授 (90251058)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords心磁図 / 虚血性心疾患 / 傷害電流 / 心電図 / 体表面マッピング / 心筋虚血
Research Abstract

In this study, we performed magnetocardiographic study for early detection of the patients with coronary artery disease. Results: There were no electric current or only a weak current of leftward, inferior direction during ST interval in healthy subjects. However, in the patients with coronary stenosis exhibited 'abnormal current' during ST interval at rest, and this 'abnormal current' increased its magnitude after exercise. The directions of this 'abnormal current' coincided with the directions of the theoretical 'injury current'. We also succeeded to detect this abnormal current three-dimensionally. Moreover, we demonstrated this abnormal current will disappear about 10 days after coronary revascularization. We concluded magnetocardiography can detect the patients with coronary stenosis very sensitively.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (14 results)

All 2012 2011 2010 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (11 results) (of which Invited: 3 results)

  • [Journal Article] Prognostic impact of plaque echolucency in combination with inflammatory biomarkers on cardiovascular outcomes of coronary artery disease patients receiving optimal medical therapy2011

    • Author(s)
      Tomoko Ishizu, Yoshihiro Seo, Tomoko Machino, Ryo Kawamura, Taizo Kimura, Nobuyuki Murakoshi, Akira Sato, Noriyuki Takeyasu, Shigeyuki Watanabe, Kazutaka Aonuma
    • Journal Title

      Atherosclerosis

      Volume: 1 Pages: 120-124

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subtraction Magnetocardiogram for Detecting Coronary2010

    • Author(s)
      Akihiko Kandori, Kuniomi Ogata, Tsuyoshi Miyashita, Hiroshi Takaki, Hideyuki Kanzaki, Syuji Hashimoto, Wataru Shimizu, Shiro Kamakura, Shigeyuki Watanabe, Kazutaka Aonuma
    • Journal Title

      Ann Noninvasive Electrocardiol

      Volume: 15 Pages: 360-368

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Subtraction Magnetocardiogram for Detecting Coronary Heart Disease2010

    • Author(s)
      Akihiko Kandori, Shigeyuki Watanabe, Kazutaka Aonuma
    • Journal Title

      Ann Noninvasive Electrocardiol

      Volume: 15 Pages: 360-368

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Magnetocardiographic findings of atrial depolarization and repolarization2012

    • Author(s)
      Yoshitsugu Nakagawa, Shigeyuki Watanabe, Masahiro Toyama, Yasuhisa Kuroda, Junya Honda, Hiroki Isono, Yukari Yoshida, Naoya Takeshi, Takeshi Inaba, Emi Arai, Yoko Sato, Akihiko Kandori
    • Organizer
      4th Asian Symposium on Magnetocardiography
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2012-08-23
    • Related Report
      2012 Final Research Report
  • [Presentation] Magnetocardiographic detection of the injury current of the patients with ischemic heart disease2012

    • Author(s)
      Shigeyuki Watanabe, Masahiro Toyama, Yoshitsugu Nakagawa, Yukari Yoshida, Naoya Takeshi, Yasuhisa Kuroda, Junya Honda, Hiroki Isono,Takeshi Inaba, Emi Arai, Yoko Sato, Akihiko Kandori
    • Organizer
      4th Asian Symposium on Magnetocardiography
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2012-08-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 潜在的心筋虚血診断における心磁図の意義2012

    • Author(s)
      渡辺重行、吉田健太郎、佐藤陽子、青沼和隆、神鳥明彦、緒方邦臣
    • Organizer
      第27回日本生体磁気学会大会
    • Place of Presentation
      東京電機大学 千住キャンパス, 東京
    • Year and Date
      2012-05-31
    • Related Report
      2012 Final Research Report
  • [Presentation] 心房細動に対するカテーテルアブレーション後の右心房磁場強度の上昇は、不整脈再発の予測因子である2012

    • Author(s)
      吉田健太郎、佐藤陽子、緒方邦臣、神鳥明彦、渡辺重行、青沼和隆
    • Organizer
      第27回日本生体磁気学会大会
    • Place of Presentation
      東京電機大学 千住キャンパス, 東京
    • Year and Date
      2012-05-31
    • Related Report
      2012 Final Research Report
  • [Presentation] Visualization of Normal and Abnormal Atrial or Ventricular Excitation Process using Magnetocardiography2010

    • Author(s)
      Shigeyuki Watanabe, Emi Arai, Yoko Sato, Yoshitsugu Nakagawa, Takeshi Inaba, Masahiro Toyama, Yasuhisa Kuroda, Toru Adachi, Akihiko Kandori, Akira Sato, Satoru Kawano, Kazutaka Aonuma
    • Organizer
      The 3rd Asian Synposium on Magnetocardiography
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2010-12-10
    • Related Report
      2012 Final Research Report
  • [Presentation] Visualization of Normal and Abnormal Atrial or Ventricular Excitation Process using Magnetocardiography2010

    • Author(s)
      Slugeytiki Watanabe
    • Organizer
      The 3rd Asian Synposium on Magnetocardiography
    • Place of Presentation
      Tsukuba(招待講演)
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Magnetocardiographical Visualization of Atrial Repolarization (Ta) Wave and its Response to Exercise2010

    • Author(s)
      Yoko Sato, Shigeyuki Watanabe, Emi Arai, Yoshitsugu Nakagawa, Takeshi Inaba, Masahiro Toyama, Yasuhisa Kuroda, Toru Adachi, Akihiko Kandori, Akira Sato, Satoru Kawano, Kazutaka Aonuma.
    • Organizer
      The 3rd Asian Synposium on Magnetocardiography
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2010-12-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Magnetocardiographic findings of atrial depolarization and repolarization

    • Author(s)
      Yoshitsugu Nakagawa
    • Organizer
      4th Asian Symposium on Magnetocardiography
    • Place of Presentation
      Shanghai, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Magnetocardiographic detection of the injury current of the patients with ischemic heart disease

    • Author(s)
      Shigeyuki Watanabe
    • Organizer
      4th Asian Symposium on Magnetocardiography
    • Place of Presentation
      Shanghai, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 潜在的心筋虚血診断における心磁図の意義

    • Author(s)
      渡辺重行
    • Organizer
      第27回日本生体磁気学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 心房細動に対するカテーテルアブレーション後の右心房磁場強度の上昇は、不整脈再発の予測因子である

    • Author(s)
      吉田健太郎
    • Organizer
      第27回日本生体磁気学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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