| Project/Area Number |
22590790
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
OGAWA Kazuei 福島県立医科大学, 医学部循環器・血液内科学講座, 教授 (40423800)
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Hitoshi 福島県立医科大学, 医学部, 准教授 (10347213)
TAKEISHI Yasuchika 福島県立医科大学, 医学部, 教授 (40272067)
TAKANO Masumi 福島県立医科大学, 医学部, 助教 (60398344)
石橋 敏幸 福島県立医科大学, 医学部, 博士研究員 (00223024)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 致死性不整脈 / 再生医療 / 移植・再生医療 / 不整脈 / 心不全 |
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| Research Abstract |
Cardiac amyloidosis is a disease having an extremely poor prognosis, and no effective treatments have been established to date. In the present study, after first implanting an implantable cardioverter-defibrillator to prevent early death associated withventricular arrhythmia, we performed and investigated the usefulness of autologous peripheral blood stem cell transplantation in patients with cardiac amyloidosis. Three among the five patients with cardiac amyloidosis for whom we have thus far performed autologous peripheral blood stem cell transplantation have achieved long-term survival, suggesting the potential usefulness of this treatment.
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