| Project/Area Number |
22590822
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | The University of Tokyo |
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Principal Investigator |
HIRATA Yasunobu 東京大学, 医学部附属病院, 特任准教授 (70167609)
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| Co-Investigator(Renkei-kenkyūsha) |
NAGATA Daisuke 東京大学, 医学部附属病院, 特任准教授 (40393194)
NISHIMATSU Hiroaki 東京大学, 医学部附属病院, 准教授 (60251295)
TAKAHASHI Masao 東京大学, 医学部附属病院, 助教 (00447418)
TANAKA Kimie 東京大学, 医学部附属病院, 助教 (30508065)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 分子血管病態学 / 移植・再生医療 / 遺伝子 / 細胞・組織 / 循環器・高血圧 / 生理活性 |
|---|
| Research Abstract |
Adipose tissue-derived stem cells (ASC) can differentiate to various kinds of cells including vascular cells. In the present studies, we showed that ASC were able to be introduced to vascular endothelial cells, and that ASC suppressed neointimal formation caused by vessel injury. ASC also improved the cavernous function. These effects were caused by paracrine effects of ASC.
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