| Project/Area Number |
22590870
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Keio University |
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Principal Investigator |
SOEJIMA Kenzo 慶應義塾大学, 医学部, 講師 (30236145)
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| Co-Investigator(Kenkyū-buntansha) |
HAMAMOTO Junko 慶應義塾大学, 医学部, 助教 (40570239)
NAOKI Katsuhiko 慶應義塾大学, 医学部, 講師 (40265806)
TERAI Hideki 慶應義塾大学, 医学部, 特任助教 (50445293)
SATO Takashi 慶應義塾大学, 医学部, 助教 (20464836)
KAWAMURA Masafumi 慶應義塾大学, 医学部, 客員教授 (70169770)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 非小細胞肺癌 / 網羅的解析 / pathway signature解析 / fibroblast growth factor-9 / microRNA / exon array / 融合遺伝子 / FGF / 腺癌 / 扁平上皮癌 / Exon array / 染色体転座 / pathway signature / PI3K |
|---|
| Research Abstract |
We performed profiling of mRNA, microRNA and DNA methylation in surgically resected 100 non-small lung cancer (NSCLC) specimens. We have identified several novel candidate molecules for the treatment of NSCLC. We also found that fibroblast growth factor-9
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