Search for genes responsible for stress-induced hypertension in SHRSPcongenic rats.
| Project/Area Number |
22590911
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Kidney internal medicine
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| Research Institution | Shimane University |
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Principal Investigator |
NABIKA Toru 島根大学, 医学部, 教授 (50180534)
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| Co-Investigator(Kenkyū-buntansha) |
HARADA Yuji 島根大学, 医学部, 准教授 (60228658)
CUI Zh 島根大学, 医学部, 助教 (50379690)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 高血圧 / モデルラット / 遺伝 / 高血圧学 / 遺伝解析 |
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| Research Abstract |
The stroke-prone spontaneously hypertensive rat (SHRSP) is a genetic model rat for essential hypertension. We previously identified that a region of chromosome 1 harbored a gene (or genes) responsible for exaggerated stress response in SHRSP. In the present study, we narrowed down the region to 1.2 Mbp and found a strong candidate gene that had a truncation in SHRSP.
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Report
(4 results)
Research Products
(46 results)
