Evaluation criteria of mild cognitive impairment by neurophysiological examination.

• Project/Area Number: 22590966
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Neurology
• Research Institution: Kanazawa Medical University
• Principal Investigator: YOSHIMURA Hiroshi 金沢医科大学, 医学部, 協力研究員 (90288845)
• Co-Investigator(Kenkyū-buntansha): MORIMOTO Shigeto 金沢医科大学, 医学部, 教授 (20150336) ; SEGAMI Natsuki 金沢医科大学, 医学部, 教授 (40148721)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 認知症 / 軽度認知障害 / 脳波周波数分析 / 長谷川式簡易知能スケール / 音楽刺激 / 画像刺激 / 脳刺激仮想空間システム / 経度認知障害

Research Abstract

We tried to make evaluation criteria of mild cognitive impairment, by using both EEG frequency analysis and psychological examination. We found that a decrease in cognitive function might be related to a decrease in the ability to generate various cortical rhythm patterns elicited by sensory stimulation and voluntary movements. Thus, it may be predictable whether mild cognitive impairment patients develop dementia, by investigating patterns of EEG frequency bands elicited sensory stimulation and voluntary movements during comfortable or uncomfortable environments.

Research Products

• [Journal Article] Age-dependent emergence of caffeine-assisted voltage oscillations in the endopiriform nucleus of rats. (2013)
  • Author(s): Yoshimura H
  • Journal Title: Neuroscience Research Volume: 75 Issue: 1-2 Pages: 16-21
  • DOI: 10.1016/j.neures.2013.02.010
  • Peer Reviewed
• [Journal Article] Correlation between stimulation strength and onset time of signal traveling within the neocortical neural circuits under caffeine application. (2011)
  • Author(s): Yoshimura H,Honjo M,Sugai T,Kaneyama K,Segami N,Kato N
  • Journal Title: Neuroscience Research. Volume: 70 Issue: 4 Pages: 370-375
  • DOI: 10.1016/j.neures.2011.05.010
  • Peer Reviewed
• [Journal Article] Influences of audio-visual environments on feeling sof deliciousness during having sweet foods: An electroencephalogram frequency analysis study. (2011)
  • Author(s): Yoshimura H,Honjo M,Sugai T,Kawabe M,Kaneyama K,Segami N,Kato N.
  • Journal Title: Nutritional Neuroscience Volume: 14 Pages: 210-215
  • Peer Reviewed
• [Journal Article] Influences of audio-visual environments on feelings of deliciousness during having sweet foods : An electroencephalogram frequency analysis study (2011)
  • Author(s): Yoshimura H
  • Journal Title: Nutritional Neuroscience Volume: 14 Pages: 210-215
  • Peer Reviewed
• [Journal Article] Evaluations of dementia by EEG frequency analysis and psychological examination. (2010)
  • Author(s): Yoshimura H,Morimoto S,Okuro M,Segami N,Kato N.
  • Journal Title: Journal of Physiology Science. Volume: 60 Issue: 5 Pages: 383-388
  • DOI: 10.1007/s12576-010-0099-6
  • NAID: 10027504700
  • Peer Reviewed
• [Journal Article] Evaluations of dementia by EEG frequency analysis and psychological examination (2010)
  • Author(s): Yoshimura H.
  • Journal Title: J Physiol Sci. Volume: 60 Pages: 383-388
  • NAID: 10027504700
  • Peer Reviewed
• [Presentation] 傍梨状皮質におけるNMDA受容体の活動に依存するオシレーションの生後発達 (2012)
  • Author(s): 吉村弘
  • Organizer: 第35回日本神経科学大会
  • Place of Presentation: 愛知県名古屋市名古屋国際会議場
  • Year and Date: 2012-09-19
• [Presentation] 傍梨状皮質におけるNMDA受容体の活動に依存するオシレーションの生後発達 (2012)
  • Author(s): 吉村弘
  • Organizer: 第３５回日本神経科学大会
  • Place of Presentation: 名古屋国際会議場 (愛知県)
• [Presentation] おいしさ感覚に対する周囲環境の影響:脳波周波数分析を用いた研究 (2011)
  • Author(s): 吉村
  • Organizer: 日本味と匂学会第45回大会
  • Place of Presentation: 石川県金沢市石川県立音楽堂
  • Year and Date: 2011-10-06
• [Presentation] カフェイン存在下で島皮質からの入力により引き起こされる内梨状核オシレーション (2011)
  • Author(s): 吉村弘
  • Organizer: 第34回日本神経科学大会
  • Place of Presentation: 神奈川県横浜市横浜パシフィコ
  • Year and Date: 2011-09-16
• [Presentation] ARBと認知症について (2010)
  • Author(s): 森本茂人
  • Organizer: 第10回MEETTHESPECIALIST
  • Place of Presentation: 富山県富山市名鉄トヤマホテル
  • Year and Date: 2010-07-13
• [Presentation] 認知症と生活習慣病 (2010)
  • Author(s): 森本茂人
  • Organizer: 第18回21世紀の認知症を考える会
  • Place of Presentation: 石川県金沢市金沢ニューグランドホテル
  • Year and Date: 2010-05-29