| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
In this study, we have tried to establish the system to evaluate the effects of CNP on iPS cells derived from skeletal dysplasia patients with dwarfism. First, we developed the culture method to induce chondrocytes from undifferentiated iPS cells in vitro. Second, we succeeded in generating iPS cells from the patient of achondroplasia. In our induction system, CNP promoted the chondrogenic differentiation of iPS cells from healthy donors. Now we are investigating the effects of CNP on the iPS cells derived from achondroplasia patient.
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