Expansion of activated NK cells from cord bloood
| Project/Area Number |
22591056
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hematology
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| Research Institution | Hokkaido University |
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Principal Investigator |
TANAKA Junji 北海道大学, 大学院・医学研究科, 准教 (50250452)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | NK細胞 / 臍帯血 / 血液内科学 / 造血幹細胞移植 / 細胞療法 |
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| Research Abstract |
We can expand NK cells more than 1,000 fold from cord blood after 3 weeks culture. These expanded NK cells can attack not only K562 leukemic cell line but also patients’ leukemic cells.
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Report
(4 results)
Research Products
(42 results)
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[Presentation]2012
Author(s)
田中淳司
Organizer
血液がんの治療つばさ共催フォーラム
Place of Presentation
札幌、北海道大学クラーク会館(北海道)
Year and Date
2012-09-01
Related Report
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[Presentation] Reduced-Intensity Versus Myeloablative Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Patients Aged Over 45 Years with AcuteLymphoblastic Leukemia (ALL) in Remission: A Study From the ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT)2012
Author(s)
Tanaka J, Kanamori H, Nishiwaki S, Ohashi K, Taniguchi S, Eto T, Nakamae H, Katayama Y, Morishima Y, Suzuki R, Kato K, Sakamaki H, Nishimoto N, Masauzi N
Organizer
54th Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
Atlanta, Georgia WorldCongress Center (USA)
Related Report
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[Presentation] Unfavorable Outcome of Single-Unit Umbilical Cord Blood Transplantation for Elderly Patients with Myelodysplastic Syndromes.2012
Author(s)
Aoki K, Ishiyama K, Itonaga H, Fukuda T, Taniguchi S, Ueda Y, Doki N, Sugio Y, Morishima Y, Nagamura T, Tanaka J, Atsuta Y, Ishikawa T, Miyazaki Y.
Organizer
54th Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
Atlanta, Georgia World Congress Center (USA)
Related Report
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[Presentation] Role of Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia in an HTLV-1Non-Endemic Area of Japan.2012
Author(s)
Shigematsu A, Tanaka J, Kobayashi N, Yasui H, Shindo M, Kakinoki Y, Iyama S, Kuroda H, Tsutsumi Y, Hashino S, Imamura M, Teshima T.
Organizer
54th Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
Atlanta, Georgia World Congress Center (USA)
Related Report
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[Presentation] Favorable Outcomes of Autologous Stem Cell Transplantation in Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in First Remission: On Behalf of the Adult Acute Lymphoblastic Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT).2012
Author(s)
Kato H, Kawase T, Kako S, Mizuta S, Ohashi K, Kurokawa M, Iwato K, Mori T, Suzuki R, Sakamaki H, Morishima Y, Tanaka J.
Organizer
54th Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
Atlanta, Georgia World Congress Center (USA)
Related Report
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[Presentation] Impact of ParentalDonor Type On Outcomes AfterHLA-Matched and HLA-MismatchedT-Cell-Replete Hematopoietic Cell Transplantation for Patients with Leukemia: A Retrospective Cohort Study.2012
Author(s)
Ichinohe T, Kanda J, Inagaki J, Inoue M, Koh K, Kikuta A, Yabe H, Tanaka J, Atsuta Y, Kanda Y.
Organizer
54th Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
Atlanta, GeorgiaWorld Congress Center (USA)
Related Report
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[Presentation] Fludarabine-Based Reduced Intensity Hematopoietic Stem Cell Transplantation (RIST) for Patients Aged 50-70 Years with Acute Lymphoblastic Leukemia (ALL) in Remission: A Study From the ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT).2011
Author(s)
Kanamori H, Kako S, Kato H, Nishiwaki S, Furukawa T, Saito M, Taniguchi S, Nakamae H, Yujiri T, Naganuma-Inoue T, Morishima Y, Suzuki R, Sakamaki H, Tanaka J.
Organizer
53rdAnnual Meeting of American Society of Hematology (ASH)
Place of Presentation
San Diego, San Diego Convention Center(USA)
Related Report
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[Presentation] Prognostic Factors of Reducing Relapse in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation From Related Donor for Acute Myeloid Leukemia: The Japan Society for Hematopoietic Cell Transplantation (JSHCT) AML Working Group.2011
Author(s)
Yano Y, Yokoyama H, Nishimura R, Fukuda T, Ogawa H, Ohashi K, Kanamori H, Tanaka J, Sakamaki H, Atsuta Y, Takami A.
Organizer
53rd Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
San Diego, San Diego ConventionCenter (USA)
Related Report
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[Presentation] Chemorefractory Disease At Transplantation, and Umbilical Cord Blood As Donor Source Were Adverse Prognostic Factors for Overall Survival After Allogeneic Stem Cell Transplantation for Follicular Lymphoma: Retrospective Study of the Japan Society of Hematopoietic Stem Cell Transplantation (JSHCT) Lymphoma Working Group2011
Author(s)
Izutsu K, Suzuki R, Kako S, Sakai R, Mori T, Yano S, Kato J, Fukuda T, Taniguchi S, Takanashi M, Morishima Y, Tanaka J, Suzumiya J. Poor Performance Status
Organizer
53rd Annual Meeting of American Society of Hematology (ASH)
Place of Presentation
San Diego, San DiegoConvention Center (USA)
Related Report
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[Presentation] Retrospective analysis for 272 patients with mature T-cell neoplasmas in Hokkaido, Japan2010
Author(s)
Shigematsu A, Kobayashi N, Minauchi K, Kobayashi H, Mori A, Masauzi N, Umehara S, Fukuhara T, Kurosawa M, Haseyama M, Hashino S, Nishio M, Kondo T, Tanaka J, Kasai M, Imamura M
Organizer
15st Congres of European Hematology Association
Place of Presentation
Barcelona, Barcelona Convention Center (Spain)
Related Report
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