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Development of transfusion products derived from hematopoietic stem cells using TNIII14 peptide

Research Project

Project/Area Number 22591066
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Hematology
Research InstitutionUniversity of Miyazaki

Principal Investigator

KUBUKI Yohko  宮崎大学, 医学部, 講師 (00284836)

Co-Investigator(Kenkyū-buntansha) MATSUNAGA Takuya  香川大学, 医学部, 教授 (70260768)
SHIMODA Kazuya  宮崎大学, 医学部, 教授 (90311844)
FUKAI Fumio  東京理科大学, 薬学部, 教授 (90124487)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords輸血学 / テネシン-C / ペプチド / 造血幹細胞 / 輸血製剤 / テネシンーC
Research Abstract

We established a novel culture system which produce a large amount of red blood cells and platelets derived from cord blood stem cells (CD34+ cells) using TNIII14 peptide and soluble fibronectin.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (3 results)

All 2012 2010

All Journal Article (1 results) Presentation (2 results)

  • [Journal Article] Potentiated activation of VLA-4 and VLA-5 accelerates proplatelet-like formation.2012

    • Author(s)
      MatsunagaT, FukaiF, KamedaT, ShideK, ShimodaH, Torii E, KamiuntenA, SekineM, YamamotoS, HidakaT, KubukiY, YokokuraS, UemuraM, MatsuokaA, WakiF, MatsumotoK, KanajiN, IshiiT, ImatakiO, DobashiH, BandohS, ShimodaK
    • Journal Title

      Ann Hematol

      Volume: 91 (10) Pages: 1633-1643

    • Related Report
      2012 Final Research Report
  • [Presentation] VLA4 と VLA5 を介したフィブロネクチンへの接着は巨核球の proplatelet 形成を促進する2010

    • Author(s)
      松永卓也,深井文雄,久冨木庸子,下田和哉,他
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Related Report
      2012 Final Research Report
  • [Presentation] VLA4とVLA5を介したフィブロネクチンへの接着は巨核球のproplatelet形成を促進する2010

    • Author(s)
      松永卓也, 深井文雄, 久冨木庸子, 下田和哉, 他
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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