A study for the etiology of the metabolic syndrome and obesity in childhood focusing on genetic background
Project/Area Number |
22591128
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Pediatrics
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Research Institution | Tottori University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
NAGATA Ikuo 鳥取大学, 医学部, 准教授 (50252846)
KANZAKI Susumu 鳥取大学, 医学部, 教授 (90224873)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | メタボリックシンドローム / 小児肥満 / 遺伝性肥満 / 遺伝素因 / インスリン感受性 / 遺伝子多型 / インスリン抵抗性 / PPARγ |
Research Abstract |
The aim of this study was to elucidate the mechanism by which the metabolic syndrome and obesity developed, especially both in Alstroem syndrome, a hereditary obesity, and genetic polymorphisms related to obesity. Several findings were obtained focusing on the relationship between insulin action and PPAR gamma stimulation, and on the relationship between SNPs for obesity-related genes and blood chemistry
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Report
(4 results)
Research Products
(53 results)
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[Journal Article] Castleman disease in a child with short stature2012
Author(s)
Hanada T, Okuno K, Okada S, Fujimoto M, Kuranobu H, Hashida Y, Ueyama J, Murakami J, Hayashi A, Hanaki K, Kanzaki S.
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Journal Title
Pediatr Int
Volume: 54(5)
Issue: 5
Pages: 720-4
DOI
Related Report
Peer Reviewed
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[Journal Article] Impact of leptin and leptin-receptor gene polymorphisms on serum lipids in Japanese obese children2010
Author(s)
Okada T, Ohzeki T, Nakagawa Y, Sugihara S, Arisaka O, Fujieda K, Asayama K, Tamai H, Hanaki K, Hara M, Kikuchi T, Kajiwara J.
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Journal Title
Acta Paediatr
Volume: 99(8)
Pages: 1213-7
Related Report
Peer Reviewed
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