| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
Regenerated bone marrow prepared using human mesenchymal cells have the ability to provide a bone marrow niche because long-term maintenance of human hematopoietic cells under the skin of the NOD mouse, an immune-deficient mouse, is possible. On the other hand, a function analysis of regenerated bone marrow prepared from adipose-derived stromal cells of mice revealed that this regenerated bone marrow can provide an environment (bone marrow niche) that is capable of maintaining the ability to self-renew as well as the multilineage potential of hematopoietic cells.
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