| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
In order to improve PCR-based MRD diagnostics using IgG/TCR genes in childhood ALL, we have measured MRD levels of bone marrow samples obtained from 100-150 patients/year with ALL, and we achieved a high frequency and sensitivities of Ig and TCR gene rearrangements as MRD PCR targets in childhood ALL. Our next study isto clarify the clinical implication of MRD levels in patients with relapsed ALL.
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