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Studies on the spectrum and pathogenesis of human bocavirus infection

Research Project

Project/Area Number 22591174
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pediatrics
Research InstitutionHokkaido University

Principal Investigator

ISHIGURO Nobuhisa  北海道大学, 北海道大学病院, 准教授 (40168216)

Co-Investigator(Kenkyū-buntansha) ARIGA Tadashi  北海道大学, 大学院・医学研究科, 教授 (60322806)
ARIKAWA Jiro  北海道大学, 大学院・医学研究科, 教授 (10142704)
KASAHARA Masanori  北海道大学, 大学院・医学研究科, 教授 (30241318)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords小児感染症学 / ヒトボカウイルス感染症 / ボカウイルス / ヒトボカウイルス / 呼吸器感染症 / 抗体価 / 胃腸炎
Research Abstract

Human bocaviruses (HBoV) 1, 2, 3, and 4 (HBoV1-4) were detected in 132 (15.5%), 5 (0.6%), 3 (0.4%), and 5 (0.6%) of 850 nasopharyngeal swab samples collected from children (0 month to 7 years old) with respiratory tract infections, respectively. Out of the 145 HBoV1-4-positive samples, 62 (42.8%) were codetected with other respiratory viruses.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (30 results)

All 2013 2012 2011 2010

All Journal Article (17 results) (of which Peer Reviewed: 11 results) Presentation (4 results) Book (9 results)

  • [Journal Article] Detection of human bocavirus 1-4 from nasopharyngeal swab samples collected from patients with respiratory tract infections.2012

    • Author(s)
      Koseki, N., S. Teramoto, M. Kaiho, R.Gomi-Endo, M. Yoshioka, Y. Takahashi, T. Nakayama, H. Sawada, M. Konno, H. Ushijima, H. Kikuta, T. Ariga, N. Ishiguro.
    • Journal Title

      J. Clin. Microbiol

      Volume: 50(6) Pages: 2118-21

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of an NKG2D ligand H60c in epidermal dendritic T cell -mediated wound repair2012

    • Author(s)
      Yoshida S, Mohamed RH, Kajikawa M, Koizumi J, Tanaka M, Fugo K, Otsuka N, Maenaka K, Yagita H, Chiba H, Kasahara M.
    • Journal Title

      J Immuno

      Volume: l188 Pages: 3972-3979

    • NAID

      10031131120

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genetic diversity of hantaviruses in Mexico: identification of three novel hantaviruses from Neotominae rodents2012

    • Author(s)
      Kariwa H, Yoshida H, Sanchez-Hernandez C, Romero-Almaraz Mde L, Almazan-Catalan JA, Ramos C, Miyashita D, Seto T, Takano A, Totani M, Murata R,Saasa N, Ishizuka M, Sanada T, Yoshii K,Yoshimatsu K, Arikawa J, Takashima I.
    • Journal Title

      Virus research

      Volume: 163 Pages: 486-494

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Activation of the brainstem precedes and outlasts the K-complex in humans2012

    • Author(s)
      Kohsaka S, Sakai T, Kohsaka M, Fukuda N, Ariga T
    • Journal Title

      Neuroscience

      Volume: 202 Pages: 243-251

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 【クローズアップ感染症】<感染性疾患の基礎的な知見の進歩・概念の変化>近年発見されたヒトボカウイルスの基礎と臨床2012

    • Author(s)
      石黒信久
    • Journal Title

      小児内科

      Volume: 44巻7号 Pages: 997-1002

    • Related Report
      2012 Final Research Report
  • [Journal Article] Detection of human bocavirus 1-4 from nasopharyngeal swab samples collected from patients with respiratory tract infections2012

    • Author(s)
      Koseki N
    • Journal Title

      J Clin Microbiol

      Volume: (掲載確定)(印刷中) Issue: 6 Pages: 2118-2121

    • DOI

      10.1128/jcm.00098-12

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 近年発見されたヒトボカウイルスの基礎と臨床2012

    • Author(s)
      石黒信久
    • Journal Title

      小児内科

      Volume: 44 Pages: 997-1002

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of KI polyomavirus and WU polyomavirus DNA by real-time polymerase chain reaction in nasopharyngeal swabs and in normal lung and lung adenocarcinoma tissues.2011

    • Author(s)
      Teramoto, S, M. Kaiho, Y. Takano, R. Endo, H. Kikuta, H. Sawa, T. Ariga, N. Ishiguro
    • Journal Title

      Microbiol Immunol

      Volume: 55(7) Pages: 525-530

    • NAID

      10031121500

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] WU Polyomavirus Infection Confirmed by Genetic and Serologic Tests in an Infant With Bronchitis2011

    • Author(s)
      Teramoto, S., N. Koseki, M. Yoshioka, Y.Matsunami, N. Yanazume, M. Nawate, T. Shikano, Y. Takahashi, H. Kikuta, N. Ishiguro
    • Journal Title

      Pediatr Infect Dis J

      Volume: 30(10) Pages: 918-918

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 【今知るべき小児感染症領域の新しい知見2011】最近注目されているウイルスヒトボカウイルス2011

    • Author(s)
      石黒信久,遠藤理香[五味],有賀正
    • Journal Title

      小児科診療

      Volume: 74巻9号 Pages: 1353-1359

    • Related Report
      2012 Final Research Report
  • [Journal Article] 【話題の呼吸器ウイルス感染症】ヒトボカウイルス感染症2011

    • Author(s)
      石黒信久
    • Journal Title

      臨床とウイルス

      Volume: 39巻4号 Pages: 184-192

    • Related Report
      2012 Final Research Report
  • [Journal Article] Detection of KI polyomavirus and WU polyomavirus DNA by real-time polymerase chain reaction in nasopharyngeal swabs and in normal lung and lung adenocarcinoma tissues2011

    • Author(s)
      Teramoto, S
    • Journal Title

      Microbiol Immunol

      Volume: 55 Issue: 7 Pages: 525-530

    • DOI

      10.1111/j.1348-0421.2011.00346.x

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] WU Polyomavirus Infection Confirmed by Genetic and Serologic Tests in an Infant With Bronchitis2011

    • Author(s)
      Teramoto, S
    • Journal Title

      Pediatr Infect Dis J

      Volume: 30 Issue: 10 Pages: 918-918

    • DOI

      10.1097/inf.0b013e3182252148

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 最近注目されているウイルス ヒトボカウイルス2011

    • Author(s)
      石黒信久
    • Journal Title

      小児科診療

      Volume: 74 Pages: 1353-1359

    • Related Report
      2011 Annual Research Report
  • [Journal Article] ヒトボカウイルス感染症2011

    • Author(s)
      石黒信久
    • Journal Title

      臨床とウイルス

      Volume: 39 Pages: 184-192

    • NAID

      10029768139

    • Related Report
      2011 Annual Research Report
  • [Journal Article] WU Polyomavirus Infection Confirmed by Genetic and Serologic Tests in an Infant With Bronchitis2011

    • Author(s)
      Teramoto, S., N.Koseki, M.Yoshioka, Y.Matsunami, N.Yanazume, M.Nawate, T.Shikano, Y.Takahashi, H.Kikuta, N.Ishiguro
    • Journal Title

      Pediatr Infect Dis J

      Volume: 30 Pages: 918-918

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ヒトボカウイルス感染症2010

    • Author(s)
      石黒信久, 遠藤理香
    • Journal Title

      日本胸部臨床

      Volume: 69 Pages: 822-833

    • NAID

      10029768139

    • Related Report
      2010 Annual Research Report
  • [Presentation] インフルエンザ治療解熱効果からみた最新の知見2012

    • Author(s)
      石黒信久
    • Organizer
      第44回日本小児感染症学会総会・学術集会
    • Place of Presentation
      西日本総合展示場・北九州国際会議場(北九州市)
    • Year and Date
      2012-11-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 新興ウイルス感染症と院内感染対策に関する話題2011

    • Author(s)
      石黒信久
    • Organizer
      第36回東日本小児科学会(茨城地方会)
    • Place of Presentation
      筑波大学(つくば市)
    • Year and Date
      2011-11-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 呼吸器感染症ウイルスに関する最近の話題とウイルス感染症からみた院内感染対策2011

    • Author(s)
      石黒信久
    • Organizer
      第15回多摩ウイルス感染症研究会
    • Place of Presentation
      京王プラザホテル新宿(東京都)
    • Year and Date
      2011-10-01
    • Related Report
      2012 Final Research Report
  • [Presentation] 多剤耐性緑膿菌感染症に対するコリスチンの有効性と使用上の注意点2010

    • Author(s)
      石黒信久
    • Organizer
      第47回緑膿菌感染症研究会
    • Place of Presentation
      札幌医科大学(札幌)
    • Year and Date
      2010-02-23
    • Related Report
      2012 Final Research Report
  • [Book] ヒトボカウイルス感染症「感染症症候群(上)病原体別感染症編」2013

    • Author(s)
      石黒信久
    • Publisher
      日本臨牀社(印刷中)
    • Related Report
      2012 Final Research Report
  • [Book] ヒトメタニューモウイルス感染症「感染症症候群(上)病原体別感染症編」2013

    • Author(s)
      石黒信久
    • Publisher
      日本臨牀社(印刷中)
    • Related Report
      2012 Final Research Report
  • [Book] ウイルス性呼吸器感染症(医学スーパーラーニングシリーズ感染症内科学)2013

    • Author(s)
      石黒信久
    • Publisher
      丸善出版株式会社
    • Related Report
      2012 Final Research Report
  • [Book] ヒトボカウイルス感染症「感染症症候群(上)病原体別感染症編」2013

    • Author(s)
      石黒信久
    • Publisher
      日本臨牀社
    • Related Report
      2012 Annual Research Report
  • [Book] アデノウイルス感染症「感染症専門医テキスト第1部解説編」2011

    • Author(s)
      石黒信久
    • Total Pages
      791
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] パルボウイルス感染症「感染症専門医テキスト第1部解説編」2011

    • Author(s)
      石黒信久
    • Total Pages
      798
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] ヒトボカウイルス感染症「感染症専門医テキスト第1部解説編」2011

    • Author(s)
      石黒信久
    • Total Pages
      801
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] ヒトメタニューモウイルス感染症「感染症専門医テキスト第1部解説編」2011

    • Author(s)
      石黒信久
    • Total Pages
      860
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] ヒトボカウイルス感染症 「感染症専門医テキスト 第1部 解説編」2011

    • Author(s)
      石黒信久
    • Total Pages
      1246
    • Publisher
      南江堂
    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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