The role of thioredoxin-1 administration to severe influenza A virus infection.
| Project/Area Number |
22591179
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Okayama University |
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Principal Investigator |
YAMASHITA Nobuko 岡山大学, 大学院・医歯薬学総合研究科, 助教 (40379798)
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| Co-Investigator(Kenkyū-buntansha) |
TSUKAHARA Hirokazu 岡山大学, 大学院・医歯薬学総合研究, 准教授 (90207340)
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | インフルエンザ / チオレドキシン / レドックス |
|---|
| Research Abstract |
Extragenous preventive administration of recombinant human thioredixin-1 significantly improved the survival rate and attenuated lung histological change in the murine model of influenza pneumonia.
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Report
(4 results)
Research Products
(4 results)
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[Journal Article] Redox-active prote administration ameliorates influenza(H1N1)-induced acute lung injury in mice.2013
Author(s)
Yashiro M, Tsukahara H, Matsukawa A, Yamada M, Fujii Y, Nagaoka Y, Tsuge M, Yamashita N, Ito T, Yamada M, Masutani H, Yodoi J, Morishima T
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Journal Title
CCare Med
Volume: 41(1)
Pages: 171-181
Related Report
Peer Reviewed
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