Tissue-specific redundancy of Hand genes in the cardiac and limbdevelopment
| Project/Area Number |
22591192
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Keio University |
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Principal Investigator |
MAEDA Jun 慶應義塾大学, 医学部, 助教 (00255506)
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAGISHI Hiroyuki 慶應義塾大学, 医学部, 講師 (40255500)
TSUCHIHASHI Takatoshi 慶應義塾大学, 医学部, 共同研究員 (10286528)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 小児循環器学 / 心臓・四肢発生 / 四肢発生 / Hand遺伝子 / 四肺発生 / 心臓発生 / Hand1遺伝子 / Hand2遺伝子 |
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| Research Abstract |
To investigate the tissue-specific role of genetic redundancy ofHand genes which encode transcription factors necessary to the cardiac and limbdevelopment, we generated genetically engineered mice harboring Hand2 gene replaced byHand1. This study demonstr
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Report
(4 results)
Research Products
(4 results)
