| Project/Area Number |
22591208
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Embryonic/Neonatal medicine
|
|---|
| Research Institution | Showa University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
NAKANO Yuya 昭和大学, 医学部, 助教 (40465224)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
|
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| Keywords | 早産児 / アディポネクチン / レプチン / 生活習慣病 / 内臓脂肪 |
|---|
| Research Abstract |
The longitudinal changes in adiponectin multimer levels differ in preterm and term infants. The ratio of high-molecular-weight adiponectin to total adiponectin in preterm infants at term- and 6 months-equivalent age was significantly lower than that in term infants at corresponding time points. Postnatal growth including fat tissue accumulation may contribute to adiponectin increases from birth to term-equivalent age, but it was not associated with the ratio of high-molecular-weight adiponectin changes in preterm infants. Further studies are needed to identify the factors that alter adiponectin multimer levels in preterm infants and determine whether they maybe associated with a higher risk of insulin resistance in the future.
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