| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Research Abstract |
To identify and characterize sweat antigen which is the major aggravating factor of atopic dermatitis, human basophil histamine releasing activity in sweat was purified by a combination of chromatographies and proteins were analyzed with mass spectrometry. Some candidate peptides for sweat antigen were obtained. To measure specific IgE against sweat antigen in patients with atopic dermatitis, a simple detection system using anti-sweat monoclonal antibody and semi-purified sweat antigen was established.
|
