Cerebral reactivity during transcranial magnetic stimulation in mood disorder and adjustment disorder

• Project/Area Number: 22591273
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Gunma University
• Principal Investigator: AOYAMA Yoshiyuki 群馬大学, 医学部, 助教 (60568351)
• Co-Investigator(Kenkyū-buntansha): TAKEI Yuichi 群馬大学, 医学部, 助教 (30455985) ; 須田 真史 群馬大学, 医学部, 医員 (30553747)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 反復経頭蓋磁気刺激 / 気分障害 / 反復経頭蓋磁気刺激法

Research Abstract

This study is the investigation of cerebral reactivity in mood disorder (major depressive disorder, bipolar I disordder, bipolar II disorder) and adjustment disorder during Repetitive transcranial magnetic stimulation (rTMS) using near infrared spectroscopy. Cerebtral reactivity during rTMS are differed in groups, and these reactivity are not relevant to mood status.

Research Products

• [Journal Article] Total and regional brain volume reductions due to the Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT): a voxel-based morphometric study (2013)
  • Author(s): Ikeda Y, Kameyama M, Narita K, Takei Y, Suda M, Aoyama Y, Yuuki N, Sakurai N, Fukuda M, Mikuni M, Amanuma M.
  • Journal Title: Prog Neuropsychopharmacol Biol Psychiatry Volume: 34(1) Pages: 244-6
  • Peer Reviewed
• [Journal Article] (2011) Associations among parenting experiences during childhood and adolescence, hypothalamus-pituitary-adrenal axis hypoactivity, and hippocampal gray matter volume reduction in young adults (2011)
  • Author(s): Narita K, Fujihara K, Takei Y, Suda M, Aoyama Y, Uehara T, Majima T, Kosaka H, Amanuma M, Fukuda M, Mikuni M.
  • Journal Title: Hum Brain Mapp Volume: 10
  • Peer Reviewed
• [Journal Article] (2011) Autistic traits and brain activation during face-to-face conversations in typically developed adults (2011)
  • Author(s): Suda M, Takei Y, Aoyama Y, Narita K, Sakurai N, Fukuda M, Mikuni M.
  • Journal Title: PLoS One Volume: 6(5)
  • Peer Reviewed
• [Journal Article] Changes in Gray Matter Volume with Rapid Body Weight Changes in Anorexia Nervosa: A Voxel-Based Morphometric Study. (2011)
  • Author(s): Suda M, Narita K, Takei Y, Aoyama Y, Takahashi K, Yuki N, Uehara T, Fukuda M, Mikuni M.
  • Journal Title: Biol Psychiatry Volume: 15;70(8)
  • Peer Reviewed
• [Journal Article] Micropolygyria in an infant born toa patient with severe anorexia nervosa: Acase report (2011)
  • Author(s): Takei Y, Suda M, Aoyama Y, Narita K, Kameyama M, Uehara T, Fukuda M, Mikuni M.
  • Journal Title: Int J Eat Disord Volume: 10 Pages: 1002-1002
  • Peer Reviewed
• [Journal Article] Volume reduction of ventromedial prefrontal cortex in bipolar II patients with rapid cycling: A voxel-based morphometric study (2011)
  • Author(s): Narita K, Suda M, Takei Y, Aoyama Y, Majima T, Kameyama M, Kosaka H, Amanuma M, Fukuda M, Mikuni M.
  • Journal Title: Prog Neuropsychopharmacol Biol Psychiatry Volume: 35(2) Pages: 439-45
  • Peer Reviewed
• [Journal Article] Autistic traits and brain activation during face-to-face conversations in typically developed adults (2011)
  • Author(s): Suda M, Takei Y, Aoyama Y, et al
  • Journal Title: PLoS One Volume: 6 Issue: 5 Pages: e20021-e20021
  • DOI: 10.1371/journal.pone.0020021
  • Peer Reviewed
• [Journal Article] Changes in Gray Matter Volume with Rapid Body Weight Changes in-Anorexia Nervosa : A Voxel-Based Morphometric Study (2011)
  • Author(s): Suda M, Narita K, Takei Y, Aoyama Y, et al
  • Journal Title: Biological Psychiatry Volume: 70 Issue: 8 Pages: 35-6
  • DOI: 10.1016/j.biopsych.2011.03.034
  • Peer Reviewed
• [Journal Article] Micropolygyria in an infant born to a patient with severe anorexia nervosa (2011)
  • Author(s): Takei Y, Suda M, Aoyama Y, Narita K, Kameyama M, Uehara T, Fukuda M, Mikuni M
  • Journal Title: a case report. Int J Eat Disord Volume: 45 Issue: 3 Pages: 447-449
  • DOI: 10.1002/eat.20927
  • Peer Reviewed
• [Journal Article] Volume reduction of ventromedial prefrontal cortex in bipolar II patient s with rapid cycling : A voxel-based morphometric study. (2011)
  • Author(s): Narita K, Suda M, Takei Y, Aoyama Y, et al.
  • Journal Title: Prog Neuropsychopharmacol Biol Psychiatry Volume: 35(2) Pages: 439-445
  • Peer Reviewed
• [Journal Article] NIRSとMEGからみた気分障害の病態生理 (2010)
  • Author(s): 青山義之,須田真史,武井雄一, 他
  • Journal Title: 臨床脳波 Volume: 52巻9号 Pages: 520-527
• [Journal Article] Relationship of parental bonding styles with gray matter volume of dorsolateral prefrontal cortex in young adults (2010)
  • Author(s): Narita K, Takei Y, Suda M, Aoyama Y, Uehara T, Kosaka H, Amanuma M, Fukuda M, Mikuni M.
  • Journal Title: Prog Neuropsychopharmacol Biol Psychiatry Volume: 34(4) Pages: 624-31
  • Peer Reviewed
• [Journal Article] Frontopolar activation during face-to-face conversation: an in situ study using near-infrared spectroscopy (2010)
  • Author(s): Suda M, Takei Y, Aoyama Y, Narita K, Sato T, Fukuda M, Mikuni M.
  • Journal Title: Neuropsychologia Volume: 48 Pages: 441-7
  • Peer Reviewed
• [Journal Article] Frontopolar activation during face-to-face conversation : an in situ study using near-infrared spectroscopy. (2010)
  • Author(s): Suda M, Takei Y, Aoyama Y, et al.
  • Journal Title: Neuropsychologia Volume: 48(2) Pages: 441-447
  • Peer Reviewed
• [Presentation] NIRSの一般的な臨床応用 (2012)
  • Author(s): 青山義之
  • Organizer: 第32回日本精神科診断学会(招待講演)
  • Place of Presentation: 沖縄,カルチャーリゾートフェストーネ
  • Year and Date: 2012-11-23
• [Presentation] NIRSの一般的な臨床応用 (2012)
  • Author(s): 青山義之
  • Organizer: 第32回日本精神科診断学会
  • Place of Presentation: 沖縄，カルチャーリゾート フェストーネ
  • Invited
• [Presentation] 統合失調症における会話の最中の脳活動のNIRSを用いた検討 (2010)
  • Author(s): 青山義之,須田真史,武井雄一, 他
  • Organizer: 第40回日本臨床神経生理学会学術大会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2010-11-02
• [Presentation] 統合失調症における会話の最中の脳活動のMRSを用いた検討 (2010)
  • Author(s): 青山義之, 須田真史, 武井雄一, 他
  • Organizer: 第40回日本臨床神経生理学会学術大会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2010-11-02