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A research for restoration possibility of damaged brain function associated with eating disorders

Research Project

Project/Area Number 22591283
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionNagoya University

Principal Investigator

SATOSHI Tanaka  名古屋大学, 医学部附属病院, 助教 (00456675)

Co-Investigator(Renkei-kenkyūsha) OZAKI Norio  名古屋大学, 大学院医学系研究科, 教授 (40281480)
KIMURA Hiroyuki  名古屋大学, 医学部附属病院, 講師 (50378030)
IIDAKA Tetsuya  名古屋大学, 大学院医学系研究科, 准教授 (70324366)
Project Period (FY) 2010-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2014: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2013: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords摂食障害 / 神経性やせ症 / 神経性無食欲症 / 精神医学 / MRI構造画像容積解析 / 質問紙 / 認知科学 / 神経心理学 / MRI volumetry / 顔認知 / 飢餓 / HRI / 公衆衛生
Outline of Final Research Achievements

We have retrieved multi-modal data from eating disordered patients with malnutrition and controls, each around 40 samples. We found in patients 1)focal decrease of cerebral volume by MRI study, 2)signature temperament and character, and their correlations with depression, 3)characteristic cognition of thinness of self image, 4)signature cerebral functioning pattern by NIRS and its correlation to social insecurity, 5)build-up of stroop effect in Simon task and 6)relationship between nutrition therapy and liver dysfunction.
Some of these findings have been submitted to professional journals, and one have been published, others have been reported orally in academic conferences. We also have utilized these for improvement of therapeutic manual for eating disorder patients.

Report

(6 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2014 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (5 results)

  • [Journal Article] Social insecurity in relation to orbitofrontal activity in patients with eating disorders: a near-infrared spectroscopy study2014

    • Author(s)
      Hiroto Katayama, Kunihiro Kohmura, Satoshi Tanaka, Miho Imaeda, Naoko Kawano, Yukihiro Noda, Kazuo Nishioka, Masahiko Ando, Branko Aleksic, Tetsuya Iidaka, Norio Ozaki
    • Journal Title

      BMC Psychiatry

      Volume: 14 Issue: 1 Pages: 173-173

    • DOI

      10.1186/1471-244x-14-173

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 顔の肥痩判断と錯視:顔の布置情報の変化に対する過小評価2014

    • Author(s)
      河野直子、矢野円郁、大川佳純、田中聡、飯高哲也、西岡和郎、尾崎紀夫
    • Organizer
      第33回基礎心理学会
    • Place of Presentation
      首都大学東京南大沢キャンパス(東京都八王子市)
    • Year and Date
      2014-12-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] 摂食障害患者の肝機能異常に関与する要因と予後に関する考察2014

    • Author(s)
      今枝美穂、加藤咲、平田陽子、片山寛人、幸村州洋、河野直子、田中聡、西岡和郎、尾崎紀夫
    • Organizer
      第18回日本摂食障害学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 摂食障害に伴う低栄養による肝逸脱酵素上昇と投与カロリーに関する後方視的検討2013

    • Author(s)
      加藤咲,今枝美穂,田中聡,片山寛人,河野直子,幸村州洋,福田奈菜,西岡和郎,尾崎紀夫
    • Organizer
      第17回日本摂食障害学会・学術集会
    • Place of Presentation
      神戸市産業振興センター(神戸市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 「摂食障害」の最近の生物学的知見と名古屋大学における治療の現状について2012

    • Author(s)
      田中聡
    • Organizer
      名古屋心身フォーラム
    • Place of Presentation
      ルブラ王山(名古屋市千種区)(招待)
    • Year and Date
      2012-02-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 近赤外線スペクトロスコピー(NIRS)を用いた神経性食思不振症の中枢神経機能障害探索2012

    • Author(s)
      田中 聡
    • Organizer
      第25回日本総合病院精神医学会総会
    • Place of Presentation
      大田区産業プラザ(東京都)
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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