| Project/Area Number |
22591285
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Nara University of Education |
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Principal Investigator |
NEGORO Hideki 奈良教育大学, 教育学部, 准教授 (80336867)
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| Co-Investigator(Kenkyū-buntansha) |
OTA Toyosaku 奈良県立医科大学, 医学部, 助教 (10553646)
澤田 将幸 奈良県立医科大学, 医学部, 助教 (60382313)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | ADHD / NIRS / 脳神経疾患 / 薬物療法 / 客観的指標 / Stroop課題 / metylphenidate徐放剤 / ノルアドレナリン再取り込み阻害薬 / atomoxetine / 前頭葉 |
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| Research Abstract |
We have proved that there are prefrontal brain dysfunction in ADHD children as compared with typical development children by near-infrared light spectroscopy (NIRS). After comparing it in before and after therapy in methylphenidate sustained-release tablet and atomoxetine for children with ADHD by the same technique,prefrontal brain dysfunction was improved after the treatment. Therefore, NIRS may be one useful measurement to evaluate the effect of pharmacotherapy.
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