Developing a low-radiation-dose high-image-quality intelligent contrast-enhanced CT system in the era of multidetector-row CT
| Project/Area Number |
22591324
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Gifu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KONDO Hiroshi 岐阜大学, 医学部付属病院, 講師 (20324311)
GOSHIMA Satoshi 岐阜大学, 医学部付属病院, 助教 (90402205)
WATANABE Haruo 岐阜大学, 医学研究科, 非常勤講師 (30456529)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | CT / インテリジェント CT / ボーラストラッキング / 低被ばく / インテリジェントCT / 多列CT / Bolus tracking / 門脈 / ヨード負荷 / 320列 / 画像ノイズ / ヘリカル撮像 |
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| Research Abstract |
The radiation exposure per a citizen in our country leads to approximately 3.7 times of the world average. Reduction of radiation exposure in CT is urgent issue, and the usefulness of low tube voltage CT has been reported. However, the reduction of radiation dose often leads to image quality deterioration by increased image noise and the contrast decrease, and the noise reduction filter has been developed for the compensation. On the other hand, side effects such as anaphylaxis or renal dysfunction related to iodine administration, but there is not evident relation between the iodine amount of 500 mg/kg - around 750 mg/kg and such adverse events. We have conducted upper abdominal CT examinations with the iodine load of 600 mg/kg, but it is believed that the dose of 521 mg/kg is sufficient for the contrast enhancement. Based on such backgrounds,we attempted to develop bolus-tracking techniques for multiple- contrast phase using two CT s in ourhospital. I also developed a program to enable the imaging at the contrast enhancement peak of organs while setting ROIs to the aorta, pancreas, and liver parenchyma. Based on the research data,we optimized the CT examinations adjusting with body habitus of patients, decreasing radiation dose, optimizing the most effective contrast phase. We also attempted to connect the system to theintelligent contrast injector. We present these results at Radiological Society of North America in2012.
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Report
(4 results)
Research Products
(46 results)
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[Journal Article] CT of the pancreas: comparison of anatomic structure depiction, image quality, and radiation exposure between 320-detector volumetric images and 64-detector helical images2011
Author(s)
Goshima S, Kanematsu M, Nishibori H, Sakurai K, Miyazawa D, Watanabe H, Kondo H, Shiratori Y, Onozuka M, Moriyama N, Bae KT
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Journal Title
Radiology
Volume: 260(1)
Pages: 139-47
Related Report
Peer Reviewed
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[Journal Article] Body Size Indexes for Optimizing IodineDose for Aortic and Hepatic Enhancement at Multidetector CT : Comparison of Total Body Weight, Lean Body Weight, and Blood Volume.2010
Author(s)
Kondo H, Kanematsu M, Goshima S, Tomita Y, Kim MJ, Moriyama N, Onozuka M, Shiratori Y, Bae KT.
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Journal Title
Radiology
Volume: 254
Pages: 163-169
Related Report
Peer Reviewed
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[Presentation] Fully Automated Quantitative Measurement of Multiple Skeletal Muscles in Torso CT Images by Use of a Statistical Shape Models.2012
Author(s)
Kamiya N, Zhou X, Kondo J, Muramatsu C, Hara T, Fujita H, Chen H, Yokoyama R, Kanematsu M, Hoshi H
Organizer
第98回北米放射線学会, シカゴ
Place of Presentation
USA
Year and Date
2012-12-25
Related Report
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[Presentation] Image Quality and Radiation in CT of the Pancreas: Comparison of 320-MDCT with and without Adaptive Iterative Dose Reduction and 64-MDCT2011
Author(s)
Goshima S, Tsuge Y, Miyazawa D, Nishibori H, Watanabe H, Yoshida M, Kawada H, Kondo H, Kanematsu M, Bae KT
Organizer
第97回北米放射線学会, シカゴ
Place of Presentation
USA
Year and Date
2011-12-25
Related Report
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[Presentation] Goshima S, Kondo H, Watanabe H, Kawada H, Mehta D, Kanematsu M, Bae KT2011
Author(s)
Goshima S, Kondo H, Watanabe H, Kawada H, Mehta D, Kanematsu M, Bae KT
Organizer
第97回北米放射線学会, シカゴ
Place of Presentation
USA
Year and Date
2011-12-25
Related Report
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