Research for development of a new technique to evaluate regional lung function using 320-detector-row MDCT

• Project/Area Number: 22591327
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Shiga University of Medical Science
• Principal Investigator: MURATA Kiyoshi 滋賀医科大学, 医学部, 教授 (20127038)
• Co-Investigator(Kenkyū-buntansha): TAKAHASHI Masashi 滋賀医科大学, 医学部, 准教授 (20179526) ; NITTA Norihisa 滋賀医科大学, 医学部, 講師 (40324587)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: エックス線・CT / 機能CT診断 / X線CT / 吸呼気CT / 定量的評価 / エアトラッピング / 呼吸気CT / X線 / CT

Research Abstract

Using data obtained with a 320-detector-row MDCT scanner, a new CT index of air trapping (attenuation volume index, AVI) in the whole lung or lobe was calculated and evaluated in 63 patients. AVI of the whole lung correlated well with FEV1.0% and proved to solve the problem of the difference of expiratory level when air trapping is evaluated with CT. AVI may become a useful tool for evaluation of regional lung function in chronic obstructive lung disease.

Research Products

• [Journal Article] Congenital lung abnormalities: a pictorial review of imaging findings (2012)
  • Author(s): Watarai F, Takahashi M, Hosoya T, Murata K
  • Journal Title: Jpn J Radiol Volume: 30 Pages: 787-797
  • NAID: 50008492392
  • Peer Reviewed
• [Journal Article] Mycobacterium kansasii pulmonary infection: CT findings in 29 cases (2012)
  • Author(s): Takahashi M, Tsukamoto H, Kawamura T, et al.
  • Journal Title: Jpn J Radiol Volume: 30 Pages: 398-406
  • NAID: 50008479764
  • Peer Reviewed
• [Journal Article] Lung image quality with 320-row wide-volume CT scans: the effect of prospective ECG-gating and comparisons with 64-row helical CT scans (2012)
  • Author(s): Yamashiro T, Miyama T, Takahashi M, et al.
  • Journal Title: Acad Radiol Volume: 19 Pages: 380-388
  • Peer Reviewed
• [Journal Article] Flat-panel detector computed tomography imaging: observer performance in detecting pulmonary nodules in comparison with conventional chest radiography and multidetector computed tomography (2012)
  • Author(s): Otani H, Nitta N, Ikeda M, et al.
  • Journal Title: J Thorac Imaging Volume: 27 Pages: 51-57
  • Peer Reviewed
• [Journal Article] Quantitative measurement of bleomycin-induced lung fibrosis in rabbits using sequential in vivo regional analysis and high-resolution computed tomography: correlation with pathologic findings (2011)
  • Author(s): Nagatani Y, Nitta Y, Otani H, et al.
  • Journal Title: Acad Radiol Volume: 18 Pages: 672-681
  • Peer Reviewed
• [Journal Article] How accurate is CT morphometry of airway? Phantom and clinical validation study. (2011)
  • Author(s): Takahashi M, et al.
  • Journal Title: Eur J Radiol Volume: In press
  • Peer Reviewed
• [Journal Article] Quantitative measurement of bleomycin-induced lung fibrosis in rabbits using sequential in vivo regional analysis and high-resolution computed tomography : Correlation with pathologic findings. (2011)
  • Author(s): Nagatani Y, et al.
  • Journal Title: Acad Radiol Volume: In press
  • Peer Reviewed
• [Journal Article] Flat-panel detector computed tomographic imaging : Observer performance in detecting pulmonary nodules in comparison with conventional chest radiography and multidetector computed tomography. (2011)
  • Author(s): Otani H, et al.
  • Journal Title: J Thorac Imaging Volume: In press
  • Peer Reviewed
• [Journal Article] Ability of chest X-ray to detect faint shadows documented as ground-glass attenuation in images of computed tomography: a comparison between flat-panel detector radiography and film-screen radiography (2010)
  • Author(s): Nagatani Y, Nitta N, Ikeda M, et al.
  • Journal Title: Eur J Radiol Volume: 75 Pages: 384-390
  • Peer Reviewed
• [Journal Article] How accurate is CT morphometry of airway? Phantom and clinical validation study
  • Author(s): Takahashi M, Okada H, Oguni N, et al.
  • Journal Title: Eur J Radiol Volume: 80 Pages: 524-530
  • Peer Reviewed
• [Presentation] Pulmonary emphysema with fibrotic wall (PEFW) seen in smokers: comparison with usual interstitial pneumonia (UIP) pattern on thin-section CT and histology (2012)
  • Author(s): Otani H, Murata K,et al
  • Organizer: Radiological Society of North America 2012
  • Place of Presentation: Chicago
• [Presentation] A new quantitative index of lobar air trapping in chronic obstructive pulmonary disease (COPD): comparison with convetional methods (2012)
  • Author(s): Nagatani Y, Murata K, et al
  • Organizer: Radiological Society of North America 2012
  • Place of Presentation: Chicago
• [Presentation] A new quantitative index of lobar air trapping in chronic obstructive lung disease (COPD): Comparison with conventional methods. (2012)
  • Author(s): Yukihiro Nagatani
  • Organizer: Radiological Society of North America 2012
  • Place of Presentation: Chicago, USA
• [Presentation] Image quality of 320-row wide volume CT scans with the diffuse lung diseases : comparison with 64-row helical CT scans. (2011)
  • Author(s): Honda O, et al.
  • Organizer: European Congress of Radiology 2011
  • Place of Presentation: Austria
  • Year and Date: 2011-03-04
• [Presentation] Classification of air density (ADAs) by MDCT: A pathological correlation with pulmonary adenocarcinoma (2009)
  • Author(s): Nitta N, et al
  • Organizer: Radiological Society of North America 2009
  • Place of Presentation: Chicago
• [Book] 低線量肺がんCT検診の知識と実務 (2010)
  • Author(s): 村田喜代史
  • Total Pages: 252
  • Publisher: オーム社