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Evaluation of myocardial ischemia with cine-tagging and first-pass perfusion MRI

Research Project

Project/Area Number 22591339
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKyushu University

Principal Investigator

NAGAO Michinobu  九州大学, 医学研究院, 准教授 (60533081)

Co-Investigator(Kenkyū-buntansha) HATAKENAKA Masamitsu  九州大学, 医学研究院, 准教授 (40253413)
MATSUO Yoshio  九州大学, 医学研究院, 助教 (50419595)
SUNAMI Shunya  九州大学, 医学研究院, 助教 (80532845)
KAMITANI Takeshi  九州大学, 医学研究院, 医員 (20419534)
HONDA Hiroshi  九州大学, 医学研究院, 教授 (90145433)
MOCHIZUKI Teruhito  愛媛大学, 医学研究院, 教授 (80145094)
HIGASHINO Hiroshi  愛媛大学, 医学研究院, 講師 (00398041)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
KeywordsMRI / タギング / 心筋パーフュージョン / 虚血性心疾患 / 心臓同期不全
Research Abstract

The purpose of this study was to quantify myocardial strain on the subendocardial and epicardial layers of the left ventricle (LV) using tagged cardiovascular magnetic resonance (CMR) and to investigate the transmural degree of contractile impairment in the chronic ischemic myocardium. In conclusion, analysis of 3T tagged MR can non-invasively quantify the transmural degree of left ventricular deformation and demonstrate predominate impairment of subendocardial strain in the chronic ischemic myocardium at rest.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (35 results)

All 2013 2012 2011 2010 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (16 results) (of which Invited: 1 results) Book (10 results) Remarks (1 results)

  • [Journal Article] Relationship between impaired cardiac sympathetic activity and spatial dyssynchrony in patients with non-ischemic heart failure: assessment by MIBG scintigraphy and tagged MRI2013

    • Author(s)
      Masato Yonezawa, Michinobu Nagao, et al
    • Journal Title

      Journal of Nuclear Cardiology

      Volume: May Issue: 4 Pages: 600-608

    • DOI

      10.1007/s12350-013-9715-1

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stress/Rest Circumferential Strain in Non-Ischemia, Ischemia, and Infarction2013

    • Author(s)
      Tomoyuki Kido, Michinobu Nagao, et al
    • Journal Title

      Circulation Journal

      Volume: 77 Issue: 5 Pages: 1235-1241

    • DOI

      10.1253/circj.CJ-12-1106

    • NAID

      10031151386

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Quantification of heterogeneity on 201Tl gated SPECT: evaluation of coronary artery disease2013

    • Author(s)
      Yasuhiro Maruoka, Michinobu Nagao, et al
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 38

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of chronic ischemic heart disease with myocardial perfusion and regional contraction analysis by contrast-enhanced 256-MSCT2013

    • Author(s)
      Ko Higuchi, Michinobu Nagao, et al
    • Journal Title

      Japanese Journal of Radiology

      Volume: 31 Issue: 2 Pages: 123-132

    • DOI

      10.1007/s11604-012-0159-3

    • NAID

      210000174320

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Quantification of heterogeneity on 201Tl gated SPECT: evaluation of coronary artery disease2013

    • Author(s)
      Yasuhiro Maruoka
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 38 Issue: 1 Pages: e7-e12

    • DOI

      10.1097/rlu.0b013e3182638e46

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subendocardial contractile impairment in chronic ischemic myocardium: assessment by strain analysis of 3T tagged CMR2012

    • Author(s)
      Michinobu Nagao, Masamitsu Hatakenaka et al
    • Journal Title

      Journal of Cardiovascular Magnetic Resonance

      Volume: 14 Issue: 1 Pages: 14-14

    • DOI

      10.1186/1532-429x-14-14

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Subendocardial contractile impairment in chronic ischemic myocardium : assessment by strain analysis of 3T tagged CMR2012

    • Author(s)
      長尾充展
    • Journal Title

      Journal of Cardiovascular Magnetic Resonance

      Volume: 14 Pages: 14-14

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional assessment of coronary artery flow using adenosine stress dual-energy CT: a preliminary study2011

    • Author(s)
      Michinobu Nagao, Teruhito Kido et al
    • Journal Title

      Internationa Journal of Cardiovascular Imaging

      Volume: 27 Issue: 3 Pages: 471-481

    • DOI

      10.1007/s10554-010-9676-2

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] The disease activity in cardiac sarcoidosis: assessment by fusion with FDG-PET and late gadolinium enhancement MRI2013

    • Author(s)
      長尾充展他
    • Organizer
      第77回日本循環器病学会総会・学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Interventricular dyssynchrony using cine-tagging MRI in adult congenital heart disease: prediction of right ventricular dysfunction2012

    • Author(s)
      Michinobu Nagao, et al
    • Organizer
      American Heart Association Scientific Sessions 2012
    • Place of Presentation
      Los Angels, USA
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Characterizing dyssynchrony by heart failure etiology: Cross-correlation analysis of myocardial strain on tagging MRI2012

    • Author(s)
      Michinobu Nagao, etal
    • Organizer
      98th Radiological Society of North America
    • Place of Presentation
      Chicago, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Characterizing dyssynchrony by heart failure etiology: Cross-correlation analysis of myocardial strain on tagging MRI2012

    • Author(s)
      Michinobu Nagao
    • Organizer
      98th Radiological Society of North America 2012
    • Place of Presentation
      Chicago, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] PhyZiodynamicsによる虚血心筋や心同期性障害の定量化の試み2012

    • Author(s)
      長尾充展
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Gated SPECTによる冠動脈疾患の左室dyssynchrony評価2011

    • Author(s)
      長尾充展
    • Organizer
      第51回日本核医学会学術総会
    • Place of Presentation
      筑波
    • Year and Date
      2011-10-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] MRIによる心不全拡張機能評価2011

    • Author(s)
      長尾充展
    • Organizer
      第39回日本磁気共鳴学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] タギングMRIによる虚血心筋の内膜下収縮機能障害評価2011

    • Author(s)
      長尾充展
    • Organizer
      第21回日本心血管画像動態学会
    • Place of Presentation
      松山市
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 256列CTによるCardiac Imagingの可能性2011

    • Author(s)
      長尾充展
    • Organizer
      第21回日本心血管画像動態学会
    • Place of Presentation
      松山市
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Subendocardial contractile impairment in myocardial ischemia: Demonstration by strain analysis of tagged MRI2011

    • Author(s)
      長尾充展他
    • Organizer
      第75回日本循環器病学会総会・学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Subendocardial contractile impairment in myocardial ischemia : Demonstration by strain analysis of tagged MRI2011

    • Author(s)
      長尾充展
    • Organizer
      第75回日本循環器病学会総会
    • Place of Presentation
      横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] Myocardial viability in Chronic Ischemic Heart : Assessment Using 256-MSCT 4-D Color-coded Perfusion Imaging2011

    • Author(s)
      長尾充展
    • Organizer
      第75回日本循環器病学会総会
    • Place of Presentation
      横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 虚血心筋の内膜下収縮障害:3TタギングMRIのストレイン解析2010

    • Author(s)
      長尾充展
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      筑波市
    • Year and Date
      2010-09-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肥大型心筋症における左室torsionと線維化の関連:3Tタギングと遅延造影MRIによる評価2010

    • Author(s)
      長尾充展
    • Organizer
      第71回日本心臓血管放射線研究会
    • Place of Presentation
      熊本市
    • Year and Date
      2010-07-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 虚血心筋の内膜下収縮障害:3TタギングMRIのストレイン解析2010

    • Author(s)
      長尾充展
    • Organizer
      第18回MR angiography研究会
    • Place of Presentation
      東京・秋葉原
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hibernating myocardium in chronic ischemic heart: demonstration by 256-MSCT 4-D colored coded perfusion imaging2010

    • Author(s)
      Michinobu Nagao, et al
    • Organizer
      American Heart Association Scientific Sessions 2010
    • Place of Presentation
      Chicago, USA
    • Related Report
      2012 Final Research Report
  • [Book] 映像メディカル9月号2012

    • Author(s)
      長尾充展
    • Total Pages
      72
    • Publisher
      産業開発機構株式会社
    • Related Report
      2012 Final Research Report
  • [Book] 映像情報メディカル9月号2012

    • Author(s)
      長尾充展
    • Total Pages
      72
    • Publisher
      産業開発機構株式会社
    • Related Report
      2012 Annual Research Report
  • [Book] Clinician MRIによる心不全左室同期性障害の評価2012

    • Author(s)
      長尾充展
    • Total Pages
      14
    • Publisher
      エーザイ株式会社
    • Related Report
      2011 Annual Research Report
  • [Book] 心CT082011

    • Author(s)
      長尾充展
    • Total Pages
      108
    • Publisher
      文光堂
    • Related Report
      2012 Final Research Report
  • [Book] 日独医報第56巻2011

    • Author(s)
      長尾充展
    • Total Pages
      103
    • Publisher
      バイエル薬品株式会社
    • Related Report
      2012 Final Research Report
  • [Book] CLINICIAN 58巻2011

    • Author(s)
      長尾充展
    • Total Pages
      118
    • Publisher
      エーザイ株式会社
    • Related Report
      2012 Final Research Report
  • [Book] InnervisionマルチモダリティによるCardiac Imaging 20112011

    • Author(s)
      長尾充展
    • Total Pages
      3
    • Publisher
      インナービジョン
    • Related Report
      2011 Annual Research Report
  • [Book] 日独医報第56巻CT・MRIによる心臓血管機能診断2011

    • Author(s)
      長尾充展
    • Total Pages
      7
    • Publisher
      バイエル薬品
    • Related Report
      2011 Annual Research Report
  • [Book] 救急医学 救急領域のマルチスライスCTマニュアル2011

    • Author(s)
      長尾充展
    • Total Pages
      252
    • Publisher
      へるす出版
    • Related Report
      2010 Annual Research Report
  • [Book] 心CT08 MDCT・MRI・SPECT・PETをいかに使い分けるか2011

    • Author(s)
      長尾充展
    • Total Pages
      108
    • Publisher
      文光堂
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.radiol.med.kyushu-u.ac.jp/lecture/bunshi

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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