| Project/Area Number |
22591344
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nagasaki University |
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Principal Investigator |
ITO Masako 長崎大学, 大学病院, 教授 (10193517)
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| Co-Investigator(Kenkyū-buntansha) |
UETANI Masataka 長崎大学, 医歯(薬)学総合研究科, 教授 (40176582)
NISHIDA Akifumi 長崎大学, 医歯(薬)学総合研究科, 助教 (30584073)
千葉 恒 長崎大学, 大学病院, 医員 (00457574)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 大腿骨 / 骨ジオメトリー / コンピュータ断層法 / 骨強度 / 骨粗鬆症 / computed tomography / computed tomography (CT) / computed tomography(CT) / 骨折リスク / 加齢変化 |
|---|
| Research Abstract |
Using clinical computed tomography (CT) and dual energy X-ray absorptiometry (DXA), hip geometry and structure-related biomechanical properties were analyzed to establish Japanese women database and to investigate clinical usefulness of hip geometry analysis using bone images. In this project, we have investigated longitudinal changes of hip geometry in Japanese postmenopausal women, characteristic of hip geometry in patients with femoral neck and trochanter fracture, and the effectiveness of osteoporotic agents (bisphosphonate and active vitamin D3 as bone anti-resorptive agents, and teriparatid as bone formative agents) on hip geometry as well as biomechanical properties.
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