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Development and clinical application of non-invasive imaging technique for cerebral ischemic area using magnetoencephalography

Research Project

Project/Area Number 22591349
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionOsaka City University

Principal Investigator

SAKAMOTO Shinichi  大阪市立大学, 大学院・医学研究科, 講師 (40464648)

Co-Investigator(Kenkyū-buntansha) TSUYUGUCHI Naohiro  大阪市立大学, 大学院・医学研究科, 准教授 (50295705)
MIKI Yukio  大阪市立大学, 大学院・医学研究科, 教授 (80303824)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords画像診断学(含放射線診断学) / 脳機能画像診断 / 脳磁図(MEG) / 脳虚血 / ischemic penumbra / PET / 脳磁図(MEG)
Research Abstract

Magnetoencephalography (MEG) was used to evaluate spontaneous neuromagnetic fields in the ischemic areas of 37 patients with unilateral internal carotid artery occlusive disease. Positron emission tomography with ^<15>O-gas inhalation (^<15>O-PET) was als

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (30 results)

All 2013 2012 2011 2010 Other

All Journal Article (13 results) (of which Peer Reviewed: 10 results) Presentation (13 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Outcomes of contemporary use of rectangular titanium stand-alone cages in anterior cervical discectomy and fusion: Cage subsidence and cervical alignment2012

    • Author(s)
      Yamagata T, Takami T, Uda T, Ikeda H, Nagata T, Sakamoto S, Tsuyuguchi N, Ohata K
    • Journal Title

      J Clin Neurosci

      Pages: 17-17

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of Cervical Spondylotic Myelopathy using Diffusion Tensor MRI Parameter at 3.0 Tesla2012

    • Author(s)
      Uda T, Takami T, Tsuyuguchi N, Sakamoto S, Yamagata T, Ikeda H, Nagata T, Ohata K
    • Journal Title

      Spine(Phila Pa 1976)

      Pages: 21-21

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] sLORETA-qm for interictal MEG epileptic spike analysis: comparison of location and quantity with equivalent dipole estimation2012

    • Author(s)
      Uda T, Tsuyuguchi N, Okumura E, Sakamoto S, Morino M, Nagata T, Ikeda H, Kunihiro N, Takami T, Ohata K
    • Journal Title

      Clin Neurophysiol

      Volume: 123(8) Pages: 1496-501

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extension of Quantifiable Modification of sLORETA for Induced Oscillatory Changes in Magnetoencephalography2012

    • Author(s)
      Uda T, Tsuyuguchi N, Okumura E, Shigihara Y, Nagata T, Terakawa Y, Sakamoto S, Ohata K
    • Journal Title

      Open Neuroimag J

      Volume: 6 Pages: 37-43

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 脳磁図の臨床応用に関する文献レビュー(第2報):虚血性脳血管障害2012

    • Author(s)
      露口尚弘,鎌田恭輔,中里信和,宇田武弘,池田英敏,坂本真一,尾崎勇,井口義信,平田雅之,亀山茂樹,石井良平,白石秀明,渡辺裕貴,橋本勲
    • Journal Title

      臨床神経生理

      Volume: 40 Pages: 195-202

    • NAID

      10031159675

    • Related Report
      2012 Final Research Report
  • [Journal Article] MRI にてdark star サインではなく脂肪沈着により bright star サインを呈した腫瘤型筋サルコイドーシスの 1 例2012

    • Author(s)
      田中紀子, 下野太郎, 坂本真一, 大竹正一郎, 根来伸夫, 三木幸雄
    • Journal Title

      臨床放射線

      Volume: 57巻10号 Pages: 1359-1363

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extension of Quantifiable Modification of sLORETA for Induced Oscillatory Changes in Magnetoencephalography.2012

    • Author(s)
      Takehiro Uda
    • Journal Title

      Open Neuroimag J

      Volume: 6 Pages: 37-43

    • DOI

      10.2174/1874440001206010037

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] sLORETA-qm for interictal MEG epileptic spike analysis: comparison of location and quantity with equivalent dipole estimation.2012

    • Author(s)
      Takehiro Uda
    • Journal Title

      Clin Neurophysiol.

      Volume: 123(8) Issue: 8 Pages: 1496-501

    • DOI

      10.1016/j.clinph.2011.12.008

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脳磁図の臨床応用に関する文献レビュー(第2報)2012

    • Author(s)
      露口尚弘
    • Journal Title

      臨床神経生理

      Volume: 40 Pages: 195-202

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Normal variation of diffusion tensor parameters of the spinal cord in healthy subjects at 3.0-Tesla2011

    • Author(s)
      Uda T., Takami T., Sakamoto S.1, Tsuyuguchi N., Yamagata T., Ohata K
    • Journal Title

      Journal of Craniovertebral Junction and Spine

      Volume: 2 Pages: 15-15

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] てんかん重積発作にてcrossed cerebellar diaschisis を来した 3 例2011

    • Author(s)
      前田裕子, 北村賀永子, 下野太郎, 坂本真一, 竹下 徹, 二ノ井照久, 溝端康光, 三木幸雄
    • Journal Title

      臨床放射線

      Volume: 56巻8号 Pages: 989-994

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 膠芽腫glioblastoma(WHO grade IV)(図説)2011

    • Author(s)
      坂本真一, 三木幸雄
    • Journal Title

      Rad Fan

      Volume: 9巻11号 Pages: 12-13

    • Related Report
      2012 Final Research Report
  • [Journal Article] びまん性星細胞腫diffuse astrocytoma(WHO grade II)(図説)2011

    • Author(s)
      坂本真一, 三木幸雄
    • Journal Title

      Rad Fan

      Volume: 9巻11号 Pages: 14-15

    • Related Report
      2012 Final Research Report
  • [Presentation] 内頸動脈閉塞性疾患の脳虚血域における神経磁気徐波活動の定量的 ROI解析2013

    • Author(s)
      坂本真一、池田英敏、露口尚弘、奥村栄一、西山英樹、鎌田 一、大畑建治、三木幸雄
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Final Research Report
  • [Presentation] Quantitative analysis on the MEG using automated ROI constitution for assessing cerebral ischemia2012

    • Author(s)
      Ikeda H, Okumura E, Sakamoto S, Nishiyama H, Kunihiro N, Ohata K, Tsuyuguchi N
    • Organizer
      18th International Conference of Biomagnetism
    • Place of Presentation
      Paris
    • Related Report
      2012 Final Research Report
  • [Presentation] 成人の脳腫瘍に間違えやすい疾患2012

    • Author(s)
      坂本真一
    • Organizer
      第48回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      長崎市
    • Related Report
      2012 Final Research Report
  • [Presentation] 自動 ROI設定法を用いた虚血脳における神経磁気活動の定量的画像化2012

    • Author(s)
      坂本真一、池田英敏、露口尚弘、宇田武弘、國廣誉世、奥村栄一、西山英樹、鎌田 一、大畑建治、三木幸雄
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Final Research Report
  • [Presentation] 自動ROI設定法を用いた虚血脳における神経磁気活動の定量的画像化2012

    • Author(s)
      坂本 真一
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜、横浜市、神奈川県
    • Related Report
      2012 Annual Research Report
  • [Presentation] Quantitative analysis on the MEG using automated ROI constitution for assessing cerebral ischemia2012

    • Author(s)
      Hidetoshi Ikeda
    • Organizer
      18th International Conference of Biomagnetism
    • Place of Presentation
      Maison de la Chimie, Paris, France
    • Related Report
      2012 Annual Research Report
  • [Presentation] 成人の脳腫瘍に間違えやすい疾患2012

    • Author(s)
      坂本真一
    • Organizer
      第48回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      長崎ブリックホール、長崎市、長崎県
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脳虚血診断としての脳磁場解析-空間フィルター法を用いたアプローチ-2011

    • Author(s)
      露口尚弘
    • Organizer
      第41回日本臨床神経生理学会・学術集会
    • Place of Presentation
      静岡県、グランシップ
    • Year and Date
      2011-11-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 自動ROI設定法を用いた虚血脳における神経磁気活動の定量的画像化2011

    • Author(s)
      坂本真一
    • Organizer
      日本脳神経外科学会第70回学術総会
    • Place of Presentation
      神奈川県、パシフィコ横浜
    • Year and Date
      2011-10-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳虚血診断としての脳磁場解析 - 空間フィルター法を用いたアプローチ2011

    • Author(s)
      露口尚弘、奥村栄一、関原謙介、坂本真一
    • Organizer
      第41回日本臨床神経生理学会・学術集会
    • Place of Presentation
      静岡市
    • Related Report
      2012 Final Research Report
  • [Presentation] イメージ・インタープリテーション・セッション2011

    • Author(s)
      坂本真一
    • Organizer
      第47回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      下関市
    • Related Report
      2012 Final Research Report
  • [Presentation] sLORETA-qm voxel-statistical estimationを用いた虚血脳における神経磁気活動の定量的画像化2010

    • Author(s)
      坂本真一
    • Organizer
      日本脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡県、福岡国際会議場
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] sLORETA-qm voxel-statistical estimation を用いた虚血脳における神経磁気活動の定量的画像2010

    • Author(s)
      坂本真一, 奥村栄一, 露口尚弘, 宇田武弘, 永田 崇, 鴫原良仁, 井出 渉, 橋本郁郎, 鎌田 一, 望月正幸, 春田康博, 三木幸雄
    • Organizer
      第69回日本脳神経外科学会総会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Book] よくわかる脳 MRI第3 版2012

    • Author(s)
      坂本真一、三木幸雄
    • Publisher
      秀潤社
    • Related Report
      2012 Final Research Report
  • [Book] 脳神経外科学改訂11 版2012

    • Author(s)
      坂本真一、三木幸雄
    • Publisher
      金芳堂
    • Related Report
      2012 Final Research Report
  • [Book] 日本医師会雑誌第140巻・特別号(1)画像診断 update2011

    • Author(s)
      三木幸雄、坂本真一
    • Related Report
      2012 Final Research Report
  • [Remarks] 研究部門ホームページ

    • URL

      http://www.med.osaka-cu.ac.jp/radiology/diag-neuro.html

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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