| Project/Area Number |
22591350
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Iwate Medical University |
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Principal Investigator |
TERASAKI Kazunori 岩手医科大学, 高エネルギー医学研究部門, 講師 (60285632)
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| Co-Investigator(Kenkyū-buntansha) |
SHOZUSHIMA Masanori 岩手医科大学, 歯科放射線学分野, 教授 (00118259)
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| Co-Investigator(Renkei-kenkyūsha) |
IWATA Ren 東北大学, サイクロトロンラジオアイソトープセンター, 教授 (60143038)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | PE T / 放射性薬剤 / PET / 核薬学 / 分析化学 |
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| Research Abstract |
In process of control was conducted to assure the efficacy and safety for several PET radiopharmaceuticals. By using this technique, the manufacturing process was optimized to keep the amounts of radionuclidic impurities to a m inimum. Significant amounts of radionuclidic impurities from the constitute metal of target chamber were detected in the target water when using a titanium target chamber. However, the impurities were almost completely eliminated subsequent purification or separated process. Solid phase extraction technique for the final formulation gave high -quality injection without impurities over rotary evaporation technique.
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