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Development of Refraction-based Phantom

Research Project

Project/Area Number 22591353
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionTokyo University of Science

Principal Investigator

ANDO Masami  東京理科大学, 総合研究機構, 教授 (30013501)

Co-Investigator(Kenkyū-buntansha) 湯浅 哲也  山形大学, 大学院・理工学研究科, 教授 (30240146)
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsエックス線 / CT / X線光学 / 屈折型コントラスト / X線暗視野法を / 軟組織描画 / ファントム / 放射光 / X線光学系 / X線暗視野法 / 屈折原理 / 屈折画像 / 2次元画像 / 3次元画像
Research Abstract

Development of visualization of human soft tissue has been performed using XDFI (X-Ray Dark-Field Imaging) that was proposed by us in 2002. Its objectives were breast, articular cartilage, carotid artery, coronary artery and iliac artery. There are two options of development; one is clinical application and the other pathological one. It will be needing to set up equipment for high contrast using phantom every day before clinical use of a system. XDFI, DEI, grating based optics have advantage of visualizing soft tissue without contrast agent over absorption contrast. They are in a strong competition. Especially XDFI has achieved imaging technique of 2D, 2.5D and 3D images. Gelatin, water and agaros were used as material of phantom. It has been proven that these can attain high contrast at 35keV. A phantom simulating human tissue is under development.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (43 results)

All 2012 2011 2010 Other

All Journal Article (18 results) (of which Peer Reviewed: 5 results) Presentation (22 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 1 results)

  • [Journal Article] 放射線RI塾「X線回折100年歴史・展望」X-Ray Diffraction of 100 Year Anniversary and Historical and Perspective2012

    • Author(s)
      安藤正海, 湯浅哲也, 大浦紀彦
    • Journal Title

      ISOTOPE News

      Volume: No. 698 Pages: 16-20

    • Related Report
      2011 Final Research Report
  • [Journal Article] Ibvestugatai of Absorbrd Radiation Dose in Refraction-Enhanced Tomography2012

    • Author(s)
      佐藤斉、島雄大介、安藤正海
    • Journal Title

      Radiation Profection Dosimetry

      Volume: 145 Pages: 40-911

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of microvessel proliferation as a tumor infiltration structure in rat glioma specimens using the diffraction-enhanced imaging in-plane CT technique2011

    • Author(s)
      Sung-Jun Seo, Naoki Sunaguchi, Masami Ando, Ki-Hwan Choi, Hong-Tae Kim, Won-Seok Chang, Ki-Hong Kim, Jong-Ki Kim
    • Journal Title

      PMB

      Volume: 57 Pages: 1251-1262

    • Related Report
      2011 Final Research Report
  • [Journal Article] Spatial Resolution of X-Ray Bright Field Imaging by X-Ray Dynamical Diffraction Theory2011

    • Author(s)
      鈴木芳文, 近浦吉則, 安藤正海
    • Journal Title

      JAP

      Volume: 110 Pages: 84902-1

    • Related Report
      2011 Final Research Report
  • [Journal Article] Refraction-contrast tomo-synthesis imaging using dark-field-imaging optics2011

    • Author(s)
      砂口尚輝, 湯浅哲也, 市原周, 安藤正海
    • Journal Title

      APL

      Volume: 99 Pages: 1037041-1

    • Related Report
      2011 Final Research Report
  • [Journal Article] Investigation of Absorbed Radiation Dose in Refraction-Enhanced Tomography2011

    • Author(s)
      佐藤斉, 島雄大介, 安藤正海
    • Journal Title

      RPD

      Volume: 145 Pages: 40-40

    • Related Report
      2011 Final Research Report
  • [Journal Article] 生体組織のためのDark Field Imaging法に基づく屈折コントラストX線CT, Refraction-Based X-Ray Computed Tomography for Biomedical Purpose using Dark Field Imaging Method2011

    • Author(s)
      砂口尚輝, 湯浅哲也, 霍慶凱, 市原周, 安藤正海
    • Journal Title

      SICE

      Volume: 47 Pages: 459-467

    • Related Report
      2011 Final Research Report
  • [Journal Article] 新X線イメージングで癌を診る!-マクロとミクロと-2011

    • Author(s)
      安藤正海, 湯浅哲也, 砂口尚輝, 遠藤登喜子
    • Journal Title

      理大科学フォーラム

      Volume: 328 Pages: 26-29

    • Related Report
      2011 Final Research Report
  • [Journal Article] 臨床応用をめざす軟組織描画法の開発:X線暗視野法の現状と将来見通し2011

    • Author(s)
      安藤正海, 霍慶凱, 酒井正樹, 湯浅哲也, 砂口尚輝, 杉山弘, 兵藤一行, 市原周, 遠藤登喜子, 森健策, 国定俊之, 平野伸一, 岩谷綱一, 島雄大介, 佐藤斉, 近浦吉則
    • Journal Title

      放射線:Ionizing Radiation

      Volume: 37-2 Pages: 111-117

    • NAID

      10027784999

    • Related Report
      2011 Final Research Report
  • [Journal Article] Convolution reconstruction algorithm for refraction-contrast computed tomography using a Laue-case analyzer for dark field imaging2011

    • Author(s)
      Naoki Sunaguchi, Tetsuya Yuasa, Qingkai Huo, Masami Ando
    • Journal Title

      Optics Letters

      Volume: 36 Pages: 391-393

    • Related Report
      2011 Final Research Report
  • [Journal Article] Statial Resolution of X-Ray Bright Field Imaging by X-Ray Dynamical Diffraction Theory2011

    • Author(s)
      鈴木義文、近裏義則、安藤正海
    • Journal Title

      J.A.P.

      Volume: 110

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Refraction-contrast tomosynthesis imaging using dark-field-imaging optics2011

    • Author(s)
      砂口尚輝、湯浅哲也、市原州、安藤正海
    • Journal Title

      Appl.Phys.Lett.

      Volume: 99

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Convolution reconstruction algorithm for refraction-contrast computed tomography using a Laue-case analyzer for dark field imaging2011

    • Author(s)
      砂口尚輝、湯浅哲也、震慶凱、安藤正海
    • Journal Title

      OPTICAL LETTERS

      Volume: 36 Pages: 391-393

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 臨床応用をめざす軟組織描画法の開発: X 線暗視野法の現状と将来見通し2011

    • Author(s)
      安藤正海, 雷慶凱, 酒井正樹, 湯浅哲也, 砂口尚輝, 杉山弘, 兵藤一行, 市原周、遠藤登喜子, 森健策, 国定俊之, 平野伸一, 岩谷綱一, 島雄大介, 佐藤斉, 近浦吉則
    • Journal Title

      放射線

      Volume: 37 Pages: 111-117

    • NAID

      10027784999

    • Related Report
      2010 Annual Research Report
  • [Journal Article] X-ray Refraction-Contrast Computed Tomography Images Using Dark-Field Imaging Optics2010

    • Author(s)
      Naoki Sunaguchi, Tetsuya Yuasa, Qingkai Huo, Shu Ichihara, Masami Ando
    • Journal Title

      Appl. Phys. Letters

      Volume: 97

    • Related Report
      2011 Final Research Report
  • [Journal Article] X-ray Refraction-Contrast Computed Tomography Images Using Dark-Field Imaging Optics2010

    • Author(s)
      砂口尚輝、湯浅哲也、窪慶凱、市原周、安藤正海
    • Journal Title

      APPLIED PHYSICS LETTERS

      Volume: 97

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 放射光マンモグラフィとX線病理学の実用化を期待して:X線光学の立場から2010

    • Author(s)
      安藤正海、審慶凱
    • Journal Title

      MIT

      Volume: 28 Pages: 90-95

    • NAID

      10026248416

    • Related Report
      2010 Annual Research Report
  • [Journal Article] シンクロトロン光を利用した非浸潤性乳管癌の3次元再構築2010

    • Author(s)
      市原周, 森健策, 湯浅哲也, 安藤正海, アントンマキシメンコ
    • Journal Title

      MIT

      Volume: 28 Pages: 102-107

    • NAID

      10026248459

    • Related Report
      2010 Annual Research Report
  • [Presentation] Recent Development of X-Ray Dark-Field Imaging2012

    • Author(s)
      安藤正海
    • Organizer
      AMSI2011
    • Place of Presentation
      西寧ホテル
    • Year and Date
      2012-08-12
    • Related Report
      2011 Final Research Report
  • [Presentation] X線病理学の確立へ向けて:X線光学系開発2012

    • Author(s)
      安藤正海, 霍慶凱, 湯浅哲也, 高橋敏男, 近浦吉則, 鈴木芳文, 砂口尚輝, 呉彦霖, 中尾悠基, 市原周, 遠藤登喜子, 湯茂竹
    • Organizer
      応用物理学会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2012-03-15
    • Related Report
      2011 Final Research Report
  • [Presentation] 乳癌臨床診断と病理診断のためのX線暗視野法の開発2012

    • Author(s)
      安藤正海
    • Organizer
      CTC研究会
    • Place of Presentation
      宮古島市市民会館
    • Year and Date
      2012-02-25
    • Related Report
      2011 Final Research Report
  • [Presentation] X線暗視野法による乳癌臨床診断と病理診断のための開発2012

    • Author(s)
      安藤正海
    • Organizer
      日本乳癌画像研究会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2012-02-04
    • Related Report
      2011 Final Research Report
  • [Presentation] X線暗視野法を用いた臨床診断と病理診断のための開発2012

    • Author(s)
      安藤正海
    • Organizer
      徳島大学仁木研究室ゼミ
    • Year and Date
      2012-01-13
    • Related Report
      2011 Final Research Report
  • [Presentation] 乳癌、風湿性関節炎早期診断成像系統的開發-基于同歩輻射的暗場法2011

    • Author(s)
      安藤正海
    • Organizer
      大学セミナー
    • Place of Presentation
      深〓大学
    • Year and Date
      2011-12-08
    • Related Report
      2011 Final Research Report
  • [Presentation] Convolution reconstruction algorithmfor refraction-contrast computed tomography using a Laue-case analyzer for dark field imaging2011

    • Author(s)
      砂口尚輝、湯浅哲也、霍慶凱、安藤正海
    • Organizer
      Optics Letters
    • Place of Presentation
      2011年
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 軟組織描画におけるX線光学系の役割とアジアにおける共同研究推進2011

    • Author(s)
      安藤正海
    • Organizer
      応用物理学会九州支部特別シンポジウム
    • Place of Presentation
      九州工業大学図書館
    • Year and Date
      2011-09-17
    • Related Report
      2011 Final Research Report
  • [Presentation] Attempt at Viewing Breast Cancer in 2-D and 3-D Mode2011

    • Author(s)
      安藤正海
    • Place of Presentation
      ソウル国立大学
    • Year and Date
      2011-06-15
    • Related Report
      2011 Final Research Report
  • [Presentation] X線暗視野法の開発と臨床応用・病理診断の現状と将来2011

    • Author(s)
      安藤正海
    • Organizer
      日本学術振興会第141委員会
    • Place of Presentation
      東京理科大学森戸記念館
    • Year and Date
      2011-02-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Dark-Field Imaging for Early diagnosis of Breast Cancer and Rheumatoid Arthritis and Its Future Aspect2011

    • Author(s)
      安藤正海
    • Organizer
      研究所コロキュウム
    • Place of Presentation
      Karlsruhe
    • Year and Date
      2011-02-04
    • Related Report
      2011 Final Research Report
  • [Presentation] Technical Development of Viewing Breast Cancer Using SR-Based Dark-Field Imaging and Its Future Aspect2011

    • Author(s)
      安藤正海
    • Organizer
      研究所セミナー
    • Place of Presentation
      新竹放射光研究所
    • Year and Date
      2011-01-21
    • Related Report
      2011 Final Research Report
  • [Presentation] International Forum on Medical Imaging in Asia, 2-D and 3-D View of Breast Cancer Using Dark-Field Imaging2011

    • Author(s)
      安藤正海
    • Organizer
      IFMIA2011
    • Place of Presentation
      那覇市市民会館テンブス館
    • Year and Date
      2011-01-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 臨床・病理診断を目指すX線暗視野法の開発:現状と将来2011

    • Author(s)
      安藤正海
    • Organizer
      日本放射学会年会
    • Year and Date
      2011-01-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Recent Development of Dark-Field Imaging for Early diagnosis of Breast Cancer and Rheumatoid Arthritis and Its Future Aspect2010

    • Author(s)
      安藤正海
    • Place of Presentation
      北京高能物理研究所
    • Year and Date
      2010-12-21
    • Related Report
      2011 Final Research Report
  • [Presentation] On Dark-Field Imaging for Early diagnosis of Breast Cancer and Rheumatoid Arthritis and Its Future Aspect - How to Approach a Clinical Mode2010

    • Author(s)
      安藤正海
    • Organizer
      AMSI2010
    • Place of Presentation
      安東両班屋敷
    • Year and Date
      2010-10-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 放射光利用軟組織イメージング-乳癌、リウマチの早期診断に向けて2010

    • Author(s)
      安藤正海
    • Organizer
      佐賀大学放射光セミナー
    • Place of Presentation
      佐賀大学
    • Year and Date
      2010-09-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 放射光利用医学イメージングのこれから2010

    • Author(s)
      安藤正海
    • Organizer
      応用物理学会セミナー
    • Place of Presentation
      長崎大学
    • Year and Date
      2010-09-15
    • Related Report
      2011 Final Research Report
  • [Presentation] X-ray Optics from Basic Theory to X-ray Dark-Field Imaging2010

    • Author(s)
      安藤正海
    • Organizer
      日韓共同セミナー
    • Place of Presentation
      富良野富良野プリンスホテル
    • Year and Date
      2010-08-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Recent Development of X-ray Dark-Field Imaging2010

    • Author(s)
      安藤正海
    • Organizer
      医用画像セミナー
    • Place of Presentation
      浦項加速器研究所
    • Year and Date
      2010-06-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Development of X-ray dark-field imaging using synchrotron radiation and its application to early diagnosis of breast cancer, bone disease and other cancers2010

    • Author(s)
      安藤正海
    • Organizer
      医用画像セミナー
    • Place of Presentation
      上海交通大学
    • Year and Date
      2010-04-23
    • Related Report
      2011 Final Research Report
  • [Presentation] X線病理学の確立へ向けたX線光学系開発

    • Author(s)
      安藤正海
    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.rs.noda.tus.ac.jp/msm-ando/index.html

    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] Nondestructive Analysis Method, Nondestructive Analysis Device, and Specific Object analyzed by the Method/Device2010

    • Inventor(s)
      安藤正海
    • Industrial Property Rights Holder
      東京理科大学
    • Acquisition Date
      2010-10-19
    • Related Report
      2011 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 透過型結晶分析体の厚さ設定方法2010

    • Inventor(s)
      安藤正海
    • Acquisition Date
      2010-04-23
    • Related Report
      2011 Final Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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