| Project/Area Number |
22591358
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
SONE Teruki 川崎医科大学, 医学部, 教授 (90179383)
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| Co-Investigator(Renkei-kenkyūsha) |
YOSHIKAWA Kunihiko 川崎医科大学, 医学部, 助教 (70454816)
JU Yong-in 川崎医療福祉大学, 医療技術学部, 講師 (00389016)
TAMADA Tsutomu 川崎医科大学, 医学部, 准教授 (40278932)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 骨粗鬆症 / X 線 CT / 有限要素解析 / 骨強度 / X線CT |
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| Research Abstract |
Assessment of bone strength is important in the diagnosis of osteoporosis. Although bone densitometry is widely used in clinical practice, it is well known that bone density itself is inadequate for the accurate estimation of bone strength. Macro- and microstructure of bone is another important property determining bone strength. Quantitative assessment of macrostructure can be achieved using dual X-ray absorptiometry and computed tomography. Finite element analysis based on computed tomography has recently been developed to improve the estimation of bone strength in vivo. In this project, we have evaluated the clinical usefulness of these methods in the diagnosis of osteoporosis.
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