| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
In patients with chronic hepatitis C, non-alcoholic steatohepatitis, and alcoholic steatohepatitis, which consist the majority of chronic liver disease in Japan, it has been shown that intrahepatic accumulation of both fat and iron plays an important role in the progression of the disease processes. The conventional MR method, however, has failed to precisely separate fat and iron at the same time. To solve this problem, we developed at first 2D sequence, multiecho FFE (mFFE), and validated its usefulness. Then, we further developed 3D sequence to overcome the weakness of mFFE, namely low spatial resolution, and successfully confirmed its usefulness in patients with chronic liver diseases.
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