| Project/Area Number |
22591375
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Kansai Medical University |
|---|
Principal Investigator |
KARIYA Shuji 関西医科大学, 医学部, 講師 (40368220)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TANIGAWA Noboru 関西医科大学, 医学部, 教授 (90227215)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
|---|
| Keywords | マイクロバブル / エックス線造影剤 / キャビテーション / 血管造影 / 陰性造影剤 / カテーテル / 炭酸ガス / 放射線診断学 / インターベンション |
|---|
| Research Abstract |
We devised a method of CO2 microbubble contrast enhancement, whereby physiological saline and CO2 gas are mixed within blood vessels to generate a large quantity of microbubbles. The generation of a large quantity of microbubbles within blood vessels promotes radiolucency and can function as a negative contrast medium. As the microbubbles do not aggregate together, and their rate of ascent is also extremely slow, this enables a large amount of microbubbles to be generated within a given volume of liquid, and there is also less chance of generating a gas-liquid two-phase flow. The objective of this study was to demonstrate that CO2 microbubble contrast enhancement depicts blood vessels when used for X-ray diagnosis.
|
