Development of adaptive radiotherapy using preliminarily-contouredstrictures and cone-beam CT for daily setup
| Project/Area Number |
22591388
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kumamoto University |
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Principal Investigator |
MURAKAMI Ryuji 熊本大学, 生命科学研究部, 教授 (90295147)
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| Co-Investigator(Renkei-kenkyūsha) |
HIRAI Toshinori 熊本大学, 生命科学研究部, 准教授 (40274724)
KATSURAGAWA Shigehiko 熊本大学, 生命科学研究部, 教授 (60021630)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 放射線治療学 / 放射線治療計画 / 画像融合 / コーンビーム CT / 放射線治療 / 画像誘導放射線治療 / 適応放射線治療 / 腫瘍体積 / コーンビームCT / 線量分布 / 放射線腫瘍学 / 治療計画 / 画像誘導 |
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| Research Abstract |
We designed a preliminary-contouring system for “double reading”in the gross tumor volume (GTV) assessment. Although there was minor system error,considerable interobserver differences for GTV contouring persisted; our system can bea valuable method for the integration of GTV contouring. The differences in prescribeddoses based on cone-beam computed tomography (CBCT) for daily setup were less than 5%. The combination of the preliminary-contouring system and CBCT-derived dose calculationcan provide adaptive radiotherapy matching with anatomical changes at each fraction.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Histopathological Changes in Parotid and Submandibular Glands of Patients Treated with Preoperative Chemoradiation Therapy for Oral Cancer2012
Author(s)
Keiko Teshima1, Ryuji Murakami, RyojiYoshida, Hideki Nakayama, AkimitsuHiraki, Toshinori Hirai, Yuji Nakaguchi,Naoko Tsujita, Etsushi Tomitaka,Mitsuhiro Furusawa, Yasuyuki Yamashita,Masanori Shinohara
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Journal Title
JRR
Volume: 53(3)
Issue: 3
Pages: 492-496
DOI
NAID
ISSN
0449-3060, 1349-9157
Related Report
Peer Reviewed
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[Journal Article] FDG-PET/CT-based Gross Tumor Volume Contouring for Radiation Therapy Planning: An Experimental Phantom Study2012
Author(s)
Ryo Toya, Ryuji Murakami, KuniyukiTashiro, Morikatsu Yoshida, FumiSakamoto, Koichi Kawanaka, ShinyaShiraishi, Yuji Nakaguchi, NaokoTsujita, Natsuo Oya, Seiji Tomiguchi,Yasuyuki Yamashita
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Journal Title
JRR
Volume: 53(2)
Issue: 2
Pages: 338-341
DOI
NAID
ISSN
0449-3060, 1349-9157
Related Report
Peer Reviewed
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[Journal Article] Longitudinal Changes over 2 Years inParotid Glands of Patients Treated withPreoperative 30-Gy Irradiation for OralCancer2011
Author(s)
Etsushi Tomitaka, Ryuji Murakami, KeikoTeshima, Tomoko Nomura, Yuji Nakaguchi,Hideki Nakayama, Mika Kitajima,Toshinori Hirai, Yushi Araki, MasanoriShinohara, Yasuyuki Yamashita
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Journal Title
Jpn J Clin Oncol
Volume: 41(4)
Pages: 503-507
DOI
Related Report
Peer Reviewed
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[Journal Article] PhaseII study of preoperative concurrentchemoradiation therapy with S-1 inpatients with T4 oral squamous cellcarcinoma2010
Author(s)
Tomoko Nomura, Ryuji Murakami, Ryo Toya,Keiko Teshima, Aya Nakahara, ToshinoriHirai, Akimitsu Hiraki, Hideki Nakayama,Yoshiyasu Yoshitake, Kazutoshi Ohta,Obayashi Takehisa, Yasuyuki Yamashita,Natsuo Oya, Masanori Shinohara
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Journal Title
Int J Radiat Oncol Biol Phys
Volume: 76(5)
Pages: 1347-1352
DOI
Related Report
Peer Reviewed
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