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Study on molecular analysis for pathological condition of liver regeneration by hepatic venous reflux disorder and its treatment approach

Research Project

Project/Area Number 22591419
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionHyogo Medical University

Principal Investigator

SUGIMOTO Takaaki  兵庫医科大学, 医学部, 研究生(研究員) (60399152)

Co-Investigator(Kenkyū-buntansha) FUJIMOTO Jiro  兵庫医科大学, 医学部, 教授 (90199373)
HIRANO Tadamichi  兵庫医科大学, 医学部, 講師 (90340968)
IIMURO Yuji  兵庫医科大学, 医学部, 教授 (30252018)
KONDO Yuichi  兵庫医科大学, 医学部, 助教 (70567213)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords肝切除シミュレーション / 鬱血性肝障害 / 肝静脈還流障害 / 3次元肝切除シミュレーション
Research Abstract

Perfusion area for the third-order portal branches was categorized to cranio-caudal type, antero-posterior type, and multiple type while conducting anatomical analysis with using a hepatectomy simulation system. The consideration for operative procedure in relation to antero-posterior type was useful to examine a rational operative procedure in accordance with hepatic functional reserve, and the consideration for operative procedure avoiding congested area with closely examining vascular anatomy contributed to the execution of safe/reliable surgery. The hepatic tissue with venous reflux disorder tended to be poor hepatic regeneration ability in comparison with tissue without reflux disorder;therefore, further analysis for the pathological condition would be required.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (10 results)

All 2012 2011 2010 Other

All Presentation (10 results)

  • [Presentation] Hepatectomy for cholangiocarcinoma using preoperative 3-D simulation system including bile duct analysis2012

    • Author(s)
      近藤 祐一
    • Organizer
      The Liver Meeting
    • Place of Presentation
      Boston, USA
    • Year and Date
      2012-11-12
    • Related Report
      2012 Final Research Report
  • [Presentation] The variation of the third-order portal branches and hepatic vein branches of right anterior segment: selection of operative procedure for liver carcinoma.2012

    • Author(s)
      栗本 亜美
    • Organizer
      The Liver Meeting
    • Place of Presentation
      Boston, USA
    • Year and Date
      2012-11-12
    • Related Report
      2012 Final Research Report
  • [Presentation] PREOPERATIVE HEPATECTOMY SIMULATION PROGRAM FOR CHOLANGIOCARCINOMA: APPLICATION TO LIVER RESECTION AND BILE DUCT RECONSTRUCTION発表代表者2012

    • Author(s)
      近藤 祐一
    • Organizer
      第47回欧州肝臓学会議
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2012-04-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 胆道癌に対する肝切除術式決定における 術前3Dシミュレーションの検討2012

    • Author(s)
      近藤祐一
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ
    • Related Report
      2012 Annual Research Report
  • [Presentation] PREOPERATIVE HEPATECTOMY SIMULATION PROGRAM FOR CHOLANGIOCARCINOMA: APPLICATION TO LIVER RESECTION AND BILE DUCT RECONSTRUCTION2012

    • Author(s)
      YUICHI KONDO
    • Organizer
      47th annual meeting of the European Association for the study of the liver
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2012 Annual Research Report
  • [Presentation] 当科における術前門脈塞栓術の適応と成績2012

    • Author(s)
      近藤祐一
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山国際会議場
    • Related Report
      2012 Annual Research Report
  • [Presentation] Hepatectomy for cholangiocarcinoma using preoperative 3-D simulation system including bile duct analysis2012

    • Author(s)
      YUICHI KONDO
    • Organizer
      第63回米国肝臓学会議(AASLD The Liver meeting 2012)
    • Place of Presentation
      BOSTON, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Application of 3D Hepatectomy SimulationProgram to Cholangiocarcinoma発表代表者2011

    • Author(s)
      近藤 祐一
    • Organizer
      第22回国際外科消化器科腫瘍科学会議
    • Place of Presentation
      TOKYO, JAPAN
    • Year and Date
      2011-11-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Application of 3D Hepatectomy SimulationProgram to Hilar Cholangiocarcinoma発表代表者2010

    • Author(s)
      近藤 祐一
    • Organizer
      The Liver Meeting
    • Place of Presentation
      Boston, USA
    • Year and Date
      2010-10-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝前区域の門脈3次分枝と肝静脈分枝形態の解析

    • Author(s)
      栗本亜美、近藤祐一
    • Organizer
      第16回臨床解剖研究会
    • Place of Presentation
      愛知産業労働センター
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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