| Project/Area Number |
22591427
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
NOMOTO Shuji 名古屋大学, 医学部附属病院, 病院講師 (40300967)
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| Co-Investigator(Kenkyū-buntansha) |
KASUYA Hideki 名古屋大学, 大学院・医学系研究科, 准教授 (00402636)
NAKAO Akimasa 名古屋大学, 大学院・医学系研究科, 教授 (70167542)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | トリプルアレイ法 / 発現アレイ / SNP アレイ / メチレーションアレイ / 消化器癌 / SNPアレイ / トリプルアレイ / メチル化アレイ / 肝細胞癌 / 胃癌 / がん関連遺伝子 / バイオマーカー |
|---|
| Research Abstract |
It has been known that cancer is a disease associated with the genetic abnormality. Various array technologies have been used to extract genes which were related tumor initiation and progression. We have devised a triple combination array analysis which was consisted the expression array, the SNP array, and the methylation array to identify tumor related genes. We could predict prognosis and/or recurrence using some of the extracted genes.
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