Prediction of response to neoadjuvant chemotherapy in esophageal cancer patients
Project/Area Number |
22591461
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Digestive surgery
|
Research Institution | University of the Ryukyus |
Principal Investigator |
SHIMOJI Hideaki 琉球大学, 大学院・医学研究科, 助教 (30305205)
|
Co-Investigator(Kenkyū-buntansha) |
NISHIMAKI Tadashi 琉球大学, 大学院・医学研究科, 教授 (70242427)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 食道外科学 / 食道癌 / 術前化学療法 / 治療効果予測 / 末梢血中循環癌細胞 / 血中メッセンジャーRNA定量 |
Research Abstract |
The aim of this study was to evaluate the prediction of response to neoadjuvant chemotherapy in esophageal cancer patients. Eight patients were enrolled in this study. In these patients, Circulating Tumor Cells were not detected by Cell Search Method. And CEA m-RNA levels were not detected by RT -PCR. SCC m-RNA levels were detected in all patients, but we could not defined the relationship between the expression of SCC m-RNA and effectiveness of the neoadjuvant chemotherapy in esophageal cancer patients.
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Report
(4 results)
Research Products
(7 results)