Therapeutic aspects from theanalysis of epithelial-mesenchymal transition (EMT) in gastric cancer.
| Project/Area Number |
22591469
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Keio University |
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Principal Investigator |
WADA Norihito 慶應義塾大学, 医学部, 講師 (40256087)
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| Co-Investigator(Kenkyū-buntansha) |
TAKEUCHI Hiroya 慶應義塾大学, 医学部, 講師 (20265838)
HAYASHIDA Tetsu 慶應義塾大学, 医学部, 助教 (80327543)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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|---|
| Keywords | 胃十二指腸外科学 / 胃癌 / 上皮間葉移行 / リンパ節転移 / HOXB9 / EMT / 浸潤転移 / リンパ管新生 / スキルス胃癌 / ＥＭＴ / MMP / TMK-1 / MKN74 / 転移浸潤 / 臨床病理 |
|---|
| Research Abstract |
We have conducted our research in order to investigate the possibility of therapeutic application of the concept of epithelial-mesenchymal transition (EMT) for the treatment of advanced gastric cancer. Gastric cancer tissue from the patient treated in our
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Report
(4 results)
Research Products
(49 results)
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[Journal Article] Clinical utility of the Revised Cardiac Risk Index in non-cardiac surgery for elderly patients: a prospective cohort study.2013
Author(s)
Hirano Y, Takeuchi H, Suda K, Oyama T, Nakamura R, Takahashi T, Kawakubo H, Wada N, Saikawa Y, Obara H, Jinno H, Hasegawa H, Tanabe M, Kitagawa Y
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[Journal Article] Adjuvant therapy with imatinib mesylate after resection of primary high-risk gastrointestinal stromal tumors in Japanese patients.2013
Author(s)
Kanda T, Nishida T, Wada N, Kobayashi O,Yamamoto M, Sawaki A, Boku N, Koseki M, Doi T, Toh Y, Kakeji Y, Sugiyama T, Komatsu Y, Kikuchi S, Ogoshi K, Katai H, Miyachi K, Hirota S, Ohtsu A
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Journal Title
Int J Clin Oncol
Volume: 18
Pages: 38-45
NAID
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[Journal Article] Intraoperative fluorescence lymphography using indocyanine green in a patient with chylothorax after esophagectomy: report of a case.2013
Author(s)
Kaburagi T, Takeuchi H, Oyama T, Nakamura R, Takahashi T, Wada N, Saikawa Y, Kamiya S, Tanaka M, Wada T, Kitagawa Y.
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Journal Title
Surg Today
Volume: 43
Issue: 2
Pages: 206-210
DOI
NAID
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Peer Reviewed
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[Journal Article] Phase I study of neoadjuvant chemoradiotherapy consisting of S-1 and cisplatin for patients with resectable advanced gastric cancer (KOGC-01)2011
Author(s)
Takahashi T, Saikawa Y, Takaishi H, Takeuchi H, Wada N, Oyama T, Fukuda K, Fukada J, Kawaguchi O, Shigematsu N, Kitagawa Y.
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Journal Title
Anticancer Res
Volume: 31
Pages: 3079-3083
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Peer Reviewed
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[Journal Article] Octreotide acetate enables the administration of chemoradiotherapy, including the oral anticancer drug S-1, in gastric cancer patients with malignant gastrointestinal obstruction2010
Author(s)
Takahashi T, Saikawa Y, Igarashi T, Tsuwano S, Kumagai K, Nakamura R, Ooyama T, Wada N, Takeuchi H, Takaishi H, Kitagawa Y.
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Journal Title
Oncology Letters
Volume: 1
Pages: 673-677
Related Report
Peer Reviewed
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[Presentation] HOXB9 expression and gastric cancer progression2012
Author(s)
Fumihiko Kato, Norihito Wada, Tetsu Hayashida, Kazumasa Fukuda, Rieko Nakamura, Tsunehiro Takahashi, Hirofumi Kawakubo, Hiroya Takeuchi, Yoshiro Saikawa, Yuko Kitagawa
Organizer
9th International Symposium on Cancer Research and Therapy
Place of Presentation
Tokyo
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[Book] 消化器単孔式腹腔鏡下手術2010
Author(s)
田邉稔, 河地茂行, 板野理, 篠田昌宏, 和田則仁, 大島剛, 小野嘉大, 谷紀幸, 上田政和, 北川雄光
Publisher
南山堂
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