| Project/Area Number |
22591532
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
ODA Katsuhiko 東北大学, 大学院・医学系研究科, 非常勤講師 (60323002)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAMOTO Shunsuke 東北大学, 大学院・医学系研究科, 准教授 (20400244)
MOTOYOSHI Naotaka 東北大学, 病院, 講師 (40375093)
SAIKI Yoshikatsu 東北大学, 大学院・医学系研究科, 教授 (50372298)
TABAYASHI Koichi 東北大学, 大学院・医学系研究科, 教授 (90142942)
AKASAKA Junetsu 東北大学, 大学病院, 講師 (80343044)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | Drug-delivery system / 循環器 / 心臓外科 / 臨床 / 虚血性心疾患 / 循環器・高血圧 / 冠動脈バイパス手術 / 吻合部狭窄 / 内膜肥厚 / ＤＤＳ |
|---|
| Research Abstract |
To develop a novel technology to prevent saphenous vein grafts stenosis in CABG, the clinical trial of external application of rapamycin-eluting film at anastomotic sites was conducted. During the study period, total 21 patients had been enrolled in this study, and no graft occlusion and no adverse effect of this film was observed. With this clinical trial, the safety and feasibility of this new DDS system have been established.
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