Anti-proliferative miRNA expression in squamous cell carcinoma of the lung: Pursue for the common therapeutic targets of the tobacco-related cancer
| Project/Area Number |
22591559
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Chiba Cancer Center (Research Institute) (2012)
Chiba University (2010-2011) |
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Principal Investigator |
MORIYA Yasumitsu 千葉県がんセンター(研究所), その他部局等, 主任医長 (90375692)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHINO Ichiro 千葉大学, 大学院・医学研究院, 教授 (40281547)
SEKI Naohiko 千葉大学, 大学院・医学研究院, 准教授 (50345013)
岡本 龍郎 千葉大学, 大学院・医学研究院, 助教 (80568626)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 肺癌 / マイクロアレイ / ゲノム / マイクロRNA / 遺伝子 / 外科 / 癌 |
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| Research Abstract |
In tobacco-related cancers including lung squamous cell carcinoma, disorder of anti-proliferative miRNA expression may be involved in the pathogenesis, and one of the miRNAs is likely to be a candidate of molecular targets. Now the referred miRNA is further analyzed for the expression status in a large series of clinical lung cancers.
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Report
(4 results)
Research Products
(14 results)
