Functional and histological analysis of brain microcirculation after subarachnoid hemorrhage
| Project/Area Number |
22591582
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HONGO Kazuhiro 信州大学, 医学部, 教授 (00135154)
MURATA Takahiro 信州大学, 医学部附属病院, 助教 (80533322)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 脳微小循環 / くも膜下出血 / カリウム / マグネシウム / レンズ核線条体動脈 |
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| Research Abstract |
We investigated the effects of changing the extracellular potassium as well as magnesium concentration in rat cerebral penetrating arterioles. It was difficult to evaluate the histological change of cerebral penetrating arterioles including Virchow-Robin space. MRI perfusion images showed no remarkable alternation of local blood flow in basal ganglia after subarachnoid hemorrhage.
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Report
(4 results)
Research Products
(16 results)
