| Project/Area Number |
22591613
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Yamaguchi University |
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Principal Investigator |
FUJII Masami 山口大学, 医学部附属病院, 准教授 (90181320)
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Michiyasu 山口大学, 大学院・医学系研究科, 教授 (80196873)
KAJIWARA Koji 山口大学, 大学院・医学系研究科, 准教授 (90253161)
IDEGUCHI Makoto 山口大学, 医学部附属病院, 助教 (10452640)
NOMURA Sadahiro 山口大学, 医学部附属病院, 講師 (20343296)
MARUTA Yuichi 山口大学, 大学院・医学系研究科, 助教 (30543970)
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| Co-Investigator(Renkei-kenkyūsha) |
KAJIWARA Koji 山口大学, 大学院・医学系研究科, 准教授 (90253161)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 脳冷却 / 脳機能マッピング / ペルチエ素子 / 言語機能 / 運動機能 / 医療機器 / 温度制御 / 覚醒下手術 / 脳局所冷却 / 冷却プローブ / 脳腫瘍 / けいれん / 脳波 |
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| Research Abstract |
An electrical cortical stimulation (ECS)is commonly used for functional mapping in awake craniotomy. However, ECS with a high intensity has a chance to induce epileptic seizures. On the other hand, focal brain cooling (FBC) has a strong suppressive effect for seizures and is able to suppress normal brain function．The aim of this study is to develop a new functional-mapping method with a FBC device. We confirmed 7℃-FBC could suppress speech and sensory functions in awake craniotomy. This phenomenon was reversible and permanent neurological deficit was not happened.
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