| Project/Area Number |
22591656
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kobe University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KUROSAKA Masahiro 神戸大学, 医学研究科, 教授 (70170115)
KUBO Seiji 神戸大学, 医学部附属病院, 助教 (30452494)
MATSUSHITA Takehiko 神戸大学, 医学部附属病院, 特定助教 (40467650)
MATSUMOTO Tomiyuki 神戸大学, 医学部附属病院, 助教 (50546588)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 幹細胞 / 再生医療 / 運動器 / 顆粒球コロニー刺激因子(G-CSF) / 骨 / 軟骨 / 靭帯 / 関節軟骨 / 靱帯 |
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| Research Abstract |
It has been reported that stem cell and multi-potent cells such as iPS cells, ES cells contribute to tissue regeneration. Granulocyte colony-stimulating factor (G-CSF）has important role recruiting stem cells. Stem cells contribute to fix injury of locomotorium (bone, joint, cartilage, ligament etc.).We hound that there were abundant vascular stem cells in injury site and G-CSF was one of the key factors to regenerate bone, cartilage and ligament.
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