Positive Effect on Rotator Cuff Repair by the Combination of Gelatin Hydrogel Sheet and Bone Morphogenetic protein 7

Research Project

Project/Area Number	22591688
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Orthopaedic surgery
Research Institution	Kyoto Prefectural University of Medicine
Principal Investigator	MORIHARA Toru 京都府立医科大学, 医学(系)研究科, 講師 (90336735)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	肩 / 腱板 / 生体吸収材料 / 成長因子 / 徐放
Research Abstract	The purpose of this study is to investigate the positive effect on rotator cuff repair by the combination of gelatin hydrogel sheet (GHS) and bone morphogenetic protein 7 (BMP-7). Rotator cuff repair was promoted by the controlled release of BMP-7 using GHS on the tendon-to-bone insertion. BMP-7 has already been used clinically and is very safe. This method will bring about shortening of rehabilitation after rotator cuff repair and it is possible that this method is valuable clinically.