| Project/Area Number |
22591733
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Okayama University |
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Principal Investigator |
TODA Yuichiro 岡山大学, 岡山大学病院, 講師 (00379786)
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| Co-Investigator(Kenkyū-buntansha) |
MORITA Kiyoshi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (40108171)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 小児心臓手術 / 急性腎傷害 / アルブミン / NGAL / 急性腎不全 / 小児 / 心臓手術 / バイオマーカー / hepcidin |
|---|
| Research Abstract |
There is no study describing incidence of acute kidney injury in pediatric cardiac surgical patients. The epidemiology for acute kidney injury in pediatric cardiac patients was found from 2 years prospective study. Besides, urinary biomarkers were also assessed for early detection of acute kidney injury. Initially, NGAL was measured for the urinary biomarker for acute kidney injury. However, NGAL level was not different between AKI and non-AKI patients. We found the increased urinary albumin level in children with acute kidney injury after pediatric cardiac surgery.
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