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Effects of the rare sugar oral administration for inflammatory organ dysfunction

Research Project

Project/Area Number 22591735
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionKagawa University

Principal Investigator

ASAGA Takehiko  香川大学, 医学部附属病院, 講師 (30359921)

Co-Investigator(Kenkyū-buntansha) MIYAWAKI Yuki  香川大学, 医学部附属病院, 助教 (10423427)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywordsシスプラチン / D-allose / 急性腎障害 / 希少糖 / アロース / 腎障害 / 腎虚血再潅 / 経口摂取
Research Abstract

D-allose attenuated ciplatin-induced TNF-alpha and MCP-1 production, neutrophil infiltration, and kidney dysfunction. However, further studies are needed to determine the effect of differences between the routes of administration.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (2 results)

All 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] D-allose Ameliorates Cisplatin-Induced Nephrotoxicity in Mice2012

    • Author(s)
      Yuki Miyawaki, Masaaki Ueki, Masaaki Ueno, Takehiko Asaga, Masaaki Tokuda, Gotaro Shirakami
    • Journal Title

      THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

      Volume: 228巻 Pages: 215-221

    • NAID

      10031127350

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] D-Allose Ameliorates Cisplatin-Induced Nephrotoxicity in Mice2012

    • Author(s)
      Yuki Miyawaki
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 228 Issue: 3 Pages: 215-221

    • DOI

      10.1620/tjem.228.215

    • NAID

      10031127350

    • ISSN
      0040-8727, 1349-3329
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed

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Published: 2010-11-30   Modified: 2019-07-29  

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